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Difference between revisions of "Plasma cell neoplasms"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Plasma cell neoplasm -- very high mag.jpg | |||
| Width = | |||
| Caption = Plasma cell neoplasm. [[H&E stain]] | |||
| Synonyms = | |||
| Micro = dyscohesive plasmacytoid cells (abundant cytoplasm, eccentrically placed nucleus), often prominent perinuclear hof, +/-nucleoli, +/-Russell bodies, +/-Dutcher bodies | |||
| Subtypes = | |||
| LMDDx = [[lymphoplasmacytic lymphoma]], [[neuroendocrine carcinoma]], poorly differentiated carcinoma, others | |||
| Stains = | |||
| IHC = CD138 +ve, CD56 +ve, CD45 -ve/+ve, CD79a +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[bone]] - [[bone marrow]] | |||
| Assdx = [[renal failure]], [[myeloma cast nephropathy]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = +/-[[anemia]], +/-hypercalcemia | |||
| Rads = +/-lytic bone lesions | |||
| Endoscopy = | |||
| Prognosis = poor | |||
| Other = | |||
| ClinDDx = [[metastatic disease]] | |||
| Tx = | |||
}} | |||
'''Plasma cell neoplasms''' arise from [[plasma cell]]s. They are encountered by anatomical pathologists on occasion. | '''Plasma cell neoplasms''' arise from [[plasma cell]]s. They are encountered by anatomical pathologists on occasion. | ||