Difference between revisions of "Nuclear atypia"

From Libre Pathology
Jump to navigation Jump to search
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Nuclear atypia''' is abnormal change of the cell nucleus.  Nuclear atypia is often seen in [[malignancy]]; however, it may be seen in benign conditions - notably inflammation.
[[Image:Colorectal adenocarcinoma - alt -- high mag.jpg|thumb|right|200px|Nuclear atypia and [[stromal desmoplasia]] in a [[colorectal adenocarcinoma]]. [[H&E stain]].]]
'''Nuclear atypia''', also '''atypical nuclei''', is an abnormal change of the cell nucleus.   


==Cancer with minimal nuclear atypia==
Nuclear atypia is often seen in [[malignancy]]; however, it may be seen in benign conditions - notably inflammation. Also, nuclear atypia in endocrine organs (known as ''[[endocrine atypia]]'') is considered normal.
 
==Cancer with no appreciable or minimal nuclear atypia==
An incomplete list:
An incomplete list:
*[[Low grade papillary urothelial carcinoma]].
*[[Low grade papillary urothelial carcinoma]].
*Some [[adenocarcinoma]]s of the upper gastrointestinal tract, e.g. [[gallbladder adenocarcinoma]], [[stomach adenocarcinoma]], [[ductal adenocarcinoma of the pancreas]].
*Some [[adenocarcinoma]]s of the upper gastrointestinal tract, e.g. [[gallbladder adenocarcinoma]], [[stomach adenocarcinoma]], [[ductal adenocarcinoma of the pancreas]].
*[[Invasive lobular carcinoma]].
*[[Invasive lobular carcinoma]].
*[[Verrucous squamous cell carcinoma]].
*Some [[malignant melanoma]]s.


==See also==
==See also==
*[[Nuclear pleomorphism]].
*[[Nuclear pleomorphism]].
*[[Reactive atypia]].
*[[Reactive atypia]].
*[[Vesicular nuclei]].
*[[Endocrine atypia]].


[[Category:Basics]]
[[Category:Basics]]

Latest revision as of 03:45, 7 June 2016

Nuclear atypia, also atypical nuclei, is an abnormal change of the cell nucleus.

Nuclear atypia is often seen in malignancy; however, it may be seen in benign conditions - notably inflammation. Also, nuclear atypia in endocrine organs (known as endocrine atypia) is considered normal.

Cancer with no appreciable or minimal nuclear atypia

An incomplete list:

See also