Difference between revisions of "Medial calcific sclerosis"

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#redirect [[Vascular_disease#Medial_calcific_sclerosis]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Medial calcific sclerosis -- intermed mag.jpg
| Width      =
| Caption    = Medial calcific sclerosis. [[H&E stain]].
| Synonyms  = Moenckeberg medial calcific sclerosis, calcific medial sclerosis of Monckeberg, Mönckeberg's arteriosclerosis (also written ''Monckeberg's arteriosclerosis'')
| Micro      = calcifications of the tunica media
| Subtypes  =
| LMDDx      = [[atherosclerosis]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[blood vessels]] - arteries
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = good
| Other      =
| ClinDDx    =
| Tx        = (nothing)
}}
'''Medial calcific sclerosis''' is a type of arteriosclerosis that has no significant clinical impact.


It is also known as '''Moenckeberg medial calcific sclerosis''', '''calcific medial sclerosis of Monckeberg''', and '''Mönckeberg's arteriosclerosis''' (also written '''Monckeberg's arteriosclerosis''').
==General==
*Usually of no clinical consequence.
==Microscopic==
Features:<ref name=Ref_Klatt7>{{Ref Klatt|7}}</ref>
*Medial calcification (purple irregular stuff on [[H&E stain|H&E]] -- calcium phosphate).
Note:
*Lumen unaffected.
DDx:
*[[Atherosclerosis]] (severe) - intimal hyperplasia with stenosis, calcifications typically in tunica intima.
===Images===
<gallery>
Image: Medial calcific sclerosis -- low mag.jpg | MCS - low mag. (WC)
Image: Medial calcific sclerosis -- intermed mag.jpg | MCS - intermed. mag. (WC)
Image: Medial calcific sclerosis -- high mag.jpg | MCS - high mag. (WC)
Image: Medial calcific sclerosis - alt -- intermed mag.jpg | MCS - intermed. mag. (WC)
Image: Medial calcific sclerosis - alt -- high mag.jpg | MCS - high mag. (WC)
</gallery>
<gallery>
Image:Calcificatio_atherosclerotica.jpg | MCS. (WC)
</gallery>
==Sign out==
<pre>
RIGHT LEG, BELOW KNEE AMPUTATION:
- MINIMAL-TO-MILD LARGE VESSEL ATHEROSCLEROSIS, SEE COMMENT.
- MEDIAL CALCIFIC SCLEROSIS.
- SKIN WITH DERMAL FIBROSIS.
COMMENT:
The sections may not be representative of disease in the distal vascular bed.
</pre>
==See also==
*[[Vascular disease]].
==References==
{{Reflist|1}}
[[Category:Cardiovascular pathology]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Latest revision as of 20:18, 10 March 2016

Medial calcific sclerosis
Diagnosis in short

Medial calcific sclerosis. H&E stain.

Synonyms Moenckeberg medial calcific sclerosis, calcific medial sclerosis of Monckeberg, Mönckeberg's arteriosclerosis (also written Monckeberg's arteriosclerosis)

LM calcifications of the tunica media
LM DDx atherosclerosis
Site blood vessels - arteries

Prognosis good
Treatment (nothing)

Medial calcific sclerosis is a type of arteriosclerosis that has no significant clinical impact.

It is also known as Moenckeberg medial calcific sclerosis, calcific medial sclerosis of Monckeberg, and Mönckeberg's arteriosclerosis (also written Monckeberg's arteriosclerosis).

General

  • Usually of no clinical consequence.

Microscopic

Features:[1]

  • Medial calcification (purple irregular stuff on H&E -- calcium phosphate).

Note:

  • Lumen unaffected.

DDx:

  • Atherosclerosis (severe) - intimal hyperplasia with stenosis, calcifications typically in tunica intima.

Images

Sign out

RIGHT LEG, BELOW KNEE AMPUTATION:
- MINIMAL-TO-MILD LARGE VESSEL ATHEROSCLEROSIS, SEE COMMENT.
- MEDIAL CALCIFIC SCLEROSIS.
- SKIN WITH DERMAL FIBROSIS.

COMMENT:
The sections may not be representative of disease in the distal vascular bed.

See also

References

  1. Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 7. ISBN 978-1416002741.