Malignant histiocytosis

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Histiocytic sarcoma is a rare tumour.

General

  • Uncommon.

Microscopic

Features:[1]

  • Malignant histiocyte-like cells:
    • Nuclear atypia.
    • Abundant eosinophilic cytoplasm.

DDx:

Image:

IHC

Features:[1]

  • CD68 +ve.

See also

References

  1. 1.0 1.1 Alexiev, BA.; Sailey, CJ.; McClure, SA.; Ord, RA.; Zhao, XF.; Papadimitriou, JC. (2007). "Primary histiocytic sarcoma arising in the head and neck with predominant spindle cell component.". Diagn Pathol 2: 7. doi:10.1186/1746-1596-2-7. PMID 17324277.