Malakoplakia

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Malakoplakia is a thingy that typically arises in the bladder.

Microscopic features:[1]

  • Large foamy macrophages with granular cytoplasm.
  • Occasional multinucleated giant cell.
  • Lymphocytes.
  • Basophilic calcified lysosomes (Michaelis-Gutmann bodies).
    • May be inside or outside of macrophages - often size of RBC or larger.

Image:

See also

References

  1. Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 1027. ISBN 0-7216-0187-1.