Difference between revisions of "Malakoplakia"

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'''Malakoplakia''' is a thingy that typically arises in the bladder.
'''Malakoplakia''' is a thingy that typically arises in the bladder.


Microscopic features:<ref>{{Ref PBoD|1027}}</ref>
==Gross==
*Yellow mass.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70719-7 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70719-7]. Accessed on: 9 September 2010.</ref>
**May mimic renal cell carcinoma.
 
==Microscopic==
Features:<ref>{{Ref PBoD|1027}}</ref>
*Large foamy macrophages with granular cytoplasm.
*Large foamy macrophages with granular cytoplasm.
*Occasional multinucleated giant cell.
*Occasional multinucleated giant cell.

Revision as of 05:16, 9 September 2010

Malakoplakia is a thingy that typically arises in the bladder.

Gross

  • Yellow mass.[1]
    • May mimic renal cell carcinoma.

Microscopic

Features:[2]

  • Large foamy macrophages with granular cytoplasm.
  • Occasional multinucleated giant cell.
  • Lymphocytes.
  • Basophilic calcified lysosomes (Michaelis-Gutmann bodies).
    • May be inside or outside of macrophages - often size of RBC or larger.

Image:

See also

References

  1. URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70719-7. Accessed on: 9 September 2010.
  2. Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 1027. ISBN 0-7216-0187-1.