Difference between revisions of "Lymphocytic interstitial pneumonia"

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(split out)
Line 19: Line 19:
*No [[vasculitis]].
*No [[vasculitis]].
*No [[necrosis]].
*No [[necrosis]].
Images:
*[http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)].
*[http://path.upmc.edu/cases/case176/micro.html LIP (upmc.edu)].


DDx:
DDx:
Line 29: Line 25:
*Nodular lymphoid hyperplasia.
*Nodular lymphoid hyperplasia.
**This is determined in part by radiology; it has nodules radiographically.
**This is determined in part by radiology; it has nodules radiographically.
===Images===
www:
*[http://www.scielo.br/img/revistas/jbpneu/v34n2/en_a02fig01.jpg LIP (scielo.br)].
*[http://path.upmc.edu/cases/case176/micro.html LIP (upmc.edu)].


==Stains==
==Stains==

Revision as of 06:35, 9 December 2014

Lymphocytic interstitial pneumonia (abbreviated LIP), also known as lymphoid interstitial pneumonia and lymphocytic interstitial pneumonitis, is an uncommon diffuse lung disease.

General

Gross

  • Location: basilar predominance.
  • Increased interstitial markings.

Microscopic

Features:[4]

  • Small mature lymphocytes (usually B cells)[5] in the interstitium of the lung.
  • Plasma cells.
  • +/-Lymphoid follicles.

Negatives:

DDx:

  • Lymphoma.
  • Follicular bronchitis/bronchiolitis.
  • Nodular lymphoid hyperplasia.
    • This is determined in part by radiology; it has nodules radiographically.

Images

www:

Stains

To exclude infection:[6]

IHC

  • May be done to exclude lymphoma.

See also

References

  1. URL: http://emedicine.medscape.com/article/299643-overview. Accessed on: 2 June 2010.
  2. Nicholson AG (August 2001). "Lymphocytic interstitial pneumonia and other lymphoproliferative disorders in the lung". Semin Respir Crit Care Med 22 (4): 409–22. doi:10.1055/s-2001-17384. PMID 16088689.
  3. Turner, BJ.; Eppes, S.; McKee, LJ.; Cosler, L.; Markson, LE. (Jan 1995). "A population-based comparison of the clinical course of children and adults with AIDS.". AIDS 9 (1): 65-72. PMID 7893443.
  4. URL: http://emedicine.medscape.com/article/299643-diagnosis. Accessed on: 2 June 2010.
  5. AFIP atlas of nontumour pathology. 2002. Vo. 2. P.265. ISBN 1-881041-79-4.
  6. URL: http://path.upmc.edu/cases/case176/dx.html. Accessed on: 8 January 2012.