Difference between revisions of "Lung carcinoma with EGFR mutation"

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*EGFR mutations are most closely associated with [[lung adenocarcinoma]].
*EGFR mutations are most closely associated with [[lung adenocarcinoma]].
*Testing indicated in [[non-small cell carcinoma]], [[adenosquamous carcinoma of the lung]], as well as [[lung adenocarcinoma]].
*Testing indicated in [[non-small cell carcinoma]], [[adenosquamous carcinoma of the lung]], as well as [[lung adenocarcinoma]].
Varies significantly by population:<ref name=pmid27738317>{{Cite journal  | last1 = Zhang | first1 = YL. | last2 = Yuan | first2 = JQ. | last3 = Wang | first3 = KF. | last4 = Fu | first4 = XH. | last5 = Han | first5 = XR. | last6 = Threapleton | first6 = D. | last7 = Yang | first7 = ZY. | last8 = Mao | first8 = C. | last9 = Tang | first9 = JL. | title = The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis. | journal = Oncotarget | volume = 7 | issue = 48 | pages = 78985-78993 | month = Nov | year = 2016 | doi = 10.18632/oncotarget.12587 | PMID = 27738317 }}</ref>
{| class="wikitable sortable"
! Population
! Prevalence
! Category
|-
| Europe
| 14%
| Geographic
|-
| China
| 38%
| Geographic
|-
| Females
| 44%
| Patient characteristics
|-
| Males
| 24%
| Patient characteristics
|-
| Non-smokers
| 49%
| Patient characteristics
|-
| Smokers or past smokers
| 22%
| Patient characteristics
|-
| Adenocarcinoma
| 38%
| Pathology
|-
| Non-adenocarcinoma
| 12%
| Pathology
|}


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Revision as of 17:42, 18 June 2017

Lung adenocarcinoma with EGFR rearrangement is a molecular subtype of lung adenocarcinoma.

General

Varies significantly by population:[1]

Population Prevalence Category
Europe 14% Geographic
China 38% Geographic
Females 44% Patient characteristics
Males 24% Patient characteristics
Non-smokers 49% Patient characteristics
Smokers or past smokers 22% Patient characteristics
Adenocarcinoma 38% Pathology
Non-adenocarcinoma 12% Pathology

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Lung core biopsy, left lower lobe:
	- EGFR mutation POSITIVE, ALK rearrangement NEGATIVE

See also

References

  1. ↑ Zhang, YL.; Yuan, JQ.; Wang, KF.; Fu, XH.; Han, XR.; Threapleton, D.; Yang, ZY.; Mao, C. et al. (Nov 2016). "The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis.". Oncotarget 7 (48): 78985-78993. doi:10.18632/oncotarget.12587. PMID 27738317.
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