Account-creators
179
edits
Difference between revisions of "Invasive breast cancer"
Jump to navigation
Jump to search
→Invasive versus non-invasive: added information from recent study on microinvasion
(→Invasive versus non-invasive: added information from recent study on microinvasion) |
|||
| (2 intermediate revisions by one other user not shown) | |||
| Line 263: | Line 263: | ||
| stains myofibroblasts & blood vessels | | stains myofibroblasts & blood vessels | ||
|} | |} | ||
Respecting findings that might indicate a more extensive search for microinvasion be undertaken in cases of pure ductal carcinoma in situ (DCIS), a recent study found 1) intermediate or high DCIS grade, 2) tumor thickness, and 3) diffuse peritumoral retraction clefts, but not such things as lymph node metastases, or HER2 score, independently increased the likelihood of finding a microinvasive component. <ref name=pmid28434924>{{cite journal |author=Mori K, Takeda M, Kodama Y, Kiyokawa H, Yasojima H, Mizutani M, Otani Y, Morikawa N, Masuda N, Mano M|title= Tumor thickness and histological features as predictors of invasive foci within preoperatively diagnosed ductal carcinoma in situ |journal=Human Pathology |volume=64 |issue= |pages=145-155 |year=2017 | pmid=28434924 |doi=10.1016/j.humpath.2017.04.004 }}</ref> | |||
===Usual ductal hyperplasia versus ductal carcinoma in situ=== | ===Usual ductal hyperplasia versus ductal carcinoma in situ=== | ||
| Line 269: | Line 271: | ||
!Disease | !Disease | ||
![[CK5/6]] | ![[CK5/6]] | ||
!ER | ![[ER]] | ||
|- | |- | ||
|UDH | |UDH | ||
| Line 287: | Line 289: | ||
===Lymph node metastases=== | ===Lymph node metastases=== | ||
Immunostaining of sentinel lymph nodes to look for isolated tumour cells and small [[lymph node metastases]] may be done. | Immunostaining of sentinel lymph nodes to look for [[isolated tumour cells]] and small [[lymph node metastases]] may be done. | ||
*CAM5.2 may be used. | *CAM5.2 may be used. | ||
*'''Not''' done routinely. | *'''Not''' done routinely. | ||