Intraductal papilloma of the breast
Jump to navigation
Jump to search
Intraductal papilloma, also papilloma, is a relatively common benign pathology of the breast.
General
- May cause nipple discharge.[1]
- Similar to papillary hidradenoma of the vulva.
Microscopic
Features:
- True papillae - nipple-shaped structures with fibrovascular cores.
- Intraductal proliferation of epithelial and myoepithelial elements.[2]
Notes:
- Lacks florid hyperplasia.[3]
- May degeneration and hyalinize to form a sclerosing papilloma.
DDx:
- Intraductal papilloma with florid epithelial hyperplasia.
- Intraductal papilloma with atypical ductal hyperplasia. †
- Intraductal papilloma with ductal carcinoma in situ. †
- Invasive papillary carcinoma of the breast.
† Size criteria are different in papillomas.
Images
Papillary hidradenoma - low mag. (WC/Nephron)
Papillary hidradenoma - very high mag. (WC/Nephron)
See also
References
- ↑ Zervoudis, S.; Iatrakis, G.; Economides, P.; Polyzos, D.; Navrozoglou, I. (Jan 2010). "Nipple discharge screening.". Womens Health (Lond Engl) 6 (1): 135-51. doi:10.2217/whe.09.81. PMID 20050819.
- ↑ "Adenoma of Nipple.". Br Med J 1 (5330): 563. Mar 1963. PMC 2123505. PMID 20789667. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2123505/?page=1.
- ↑ URL: http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html. Accessed on: 6 August 2011.