Interval appendectomy

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Interval appendectomy is an appendectomy following the presentation of acute appendicitis.[1]

General

  • Done to exclude neoplasm and recurrent appendicitis.[2]
  • Histologically may mimic Crohn's disease.[3]

Microscopic

Features:

  • Muscularis propria eosinophils and/or plasma cells.
  • +/-Muscularis propria neutrophils.
  • +/-Granulatous inflammation.

DDx:

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Vermiform Appendix, Appendectomy:
	- Benign appendix with mild mixed muscularis inflammation (plasma cells, eosinophils, possible rare neutrophils), see comment.

Comment:
The operative report describes an interval appendectomy; the finds would be compatible with that.

See also

References

  1. Quartey B (July 2012). "Interval appendectomy in adults: A necessary evil?". J Emerg Trauma Shock 5 (3): 213–6. doi:10.4103/0974-2700.99683. PMC 3440885. PMID 22988397. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440885/.
  2. de Jonge J, Bolmers MDM, Musters GD, van Rossem CC, Bemelman WA, van Geloven AAW (July 2019). "Predictors for interval appendectomy in non-operatively treated complicated appendicitis". Int J Colorectal Dis 34 (7): 1325–1332. doi:10.1007/s00384-019-03303-4. PMID 31175422.
  3. 3.0 3.1 Guo G, Greenson JK (August 2003). "Histopathology of interval (delayed) appendectomy specimens: strong association with granulomatous and xanthogranulomatous appendicitis". Am J Surg Pathol 27 (8): 1147–51. doi:10.1097/00000478-200308000-00013. PMID 12883248.