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Difference between revisions of "Hepatocellular carcinoma"
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Hepatocellular carcinoma (view source)
Revision as of 22:33, 11 November 2013
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Hepatocellular_carcinoma_intermed_mag.jpg | |||
| Width = | |||
| Caption = Hepatocellular carcinoma. | |||
| Micro = | |||
| Subtypes = sclerosing HCC, fibrolamellar HCC | |||
| LMDDx = [[cholangiocarcinoma]], occasionally [[liver metastasis]] | |||
| Stains = reticulin (thickened liver plate) | |||
| IHC = CD34 +ve sinusoids, HepPar-1 +ve (usu.), AFP +ve (usu.), CK8/18 +ve, glypican-3 +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = usu. cirrhosis (micronodular or macronodular) | |||
| Grossing = | |||
| Site = [[liver]] - see [[liver neoplasms]] | |||
| Assdx = causes of [[cirrhosis]], e.g. chronic [[alcoholism]], [[Hepatitis C]], [[Hepatitis B]], [[hereditary hemochromatosis]], others | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = most common primary liver tumour, less common than metastases | |||
| Bloodwork = +/-AFP elevation | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = moderate to poor | |||
| Other = | |||
| ClinDDx = [[liver metastasis]], other liver tumours | |||
}} | |||
'''Hepatocellular carcinoma''', abbreviated '''HCC''', is a common primary malignant liver tumour that most often arises in the context of [[cirrhosis]]. | '''Hepatocellular carcinoma''', abbreviated '''HCC''', is a common primary malignant liver tumour that most often arises in the context of [[cirrhosis]]. | ||