Gynecomastoid hyperplasia
Jump to navigation
Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Gynecomastoid hyperplasia | |
---|---|
Diagnosis in short | |
Gynecomastoid hyperplasia. H&E stain. | |
| |
Synonyms | gynecomastia |
| |
LM | moderate hyperplasia - glands have more than 2 cell layers, "budding" (cells jut into the lumen, buds may be multicellular -- but narrower toward the centre of the lumen), stromal palor |
LM DDx | Micropapillary DCIS |
Site | breast |
| |
Associated Dx | Liver failure, Klinefelter syndrome, testicular estrogen-producing germ cell tumour |
Signs | excessive breast tissue |
Prognosis | benign |
Treatment | surgery |
Gynecomastoid hyperplasia, also gynecomastia, is a benign pathology of the breast classically seen in young men.
General
- Benign enlargement of breasts in males.
- Histologic changes may be seen in females.[1]
May be seen in the context of:
- Liver failure.
- Klinefelter syndrome.
- Testicular estrogen-producing germ cell tumour.
Gross
- Excessive breast tissue in males.
Images
Microscopic
Features:[1]
- Moderate hyperplasia.
- Glands have more than 2 cell layers.
- "Budding" - individual cells jut into the lumen - key feature.
- Buds may be multicellular; however, narrower toward the centre of the lumen.
- Stromal palor.[2]
DDx:
- Micropapillary DCIS - buds not narrower toward the centre of the lumen.
Images
www:
Sign out
A. Breast Tissue (60 g), Right, Excision: - Benign breast tissue. B. Breast Tissue (70 g), Left, Excision: - Benign breast tissue.
Alternate
Left Chest Mass, Excision: - Breast tissue with gynecomastoid hyperplasia. - NEGATIVE for malignancy.
Micro
The sections show breast tissue with epithelial hyperplasia and stromal palor. The architecture is normal. Epithelial budding is present. Significant atypia is absent.
See also
References
- ↑ 1.0 1.1 URL: http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm. Accessed on: 16 November 2011.
- ↑ URL: http://radiology.uchc.edu/eAtlas/Breast/1693.htm. Accessed on: 16 November 2011.