Difference between revisions of "Eosinophil"

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[[Image:Eosinophilic_colitis_--_very_high_mag.jpg|thumb|right|350px|Eosinophils in [[eosinophilic colitis]]. [[H&E stain]].]]
'''Eosinophil''' is a common type of white blood cell.  
'''Eosinophil''' is a common type of white blood cell.  


==Microscopic==
==General==
Features:
===Diseases with many eosinophils===
*Bilobed nucleus.
*Granular eosinophilic cytoplasm.
 
DDx:
*Paneth cells.
 
==Disease with many eosinophils==
*Infection - esp. [[fungus|fungal]].
*Infection - esp. [[fungus|fungal]].
*[[Drug reaction]].
*[[Drug reaction]].
*[[Inflammatory fibroid polyp]].
*[[Inflammatory fibroid polyp]].
*[[Hodgkin lymphoma]].
*[[Eosinophilic granulomatosis with polyangiitis]] (Churg-Strauss syndrome).
*[[Churg-Strauss syndrome]].
*[[Asthma]].
*[[Kimura disease]].
*[[Inflammatory bowel disease]].
*[[Langerhans cell histiocytosis]].
*[[Langerhans cell histiocytosis]].
*[[Kimura disease]].
*Hypereosinophilic syndrome (HES).<ref>{{Cite journal  | last1 = Podjasek | first1 = JC. | last2 = Butterfield | first2 = JH. | title = Mortality in hypereosinophilic syndrome: 19 years of experience at Mayo Clinic with a review of the literature. | journal = Leuk Res | volume = 37 | issue = 4 | pages = 392-5 | month = Apr | year = 2013 | doi = 10.1016/j.leukres.2012.12.016 | PMID = 23332454 }}</ref>
*[[Asthma]].
 
====Neoplastic related====
*Eosinophilic myeloproliferative neoplasm.<ref>{{Cite journal  | last1 = Noel | first1 = P. | last2 = Mesa | first2 = RA. | title = Eosinophilic myeloid neoplasms. | journal = Curr Opin Hematol | volume = 20 | issue = 2 | pages = 157-62 | month = Mar | year = 2013 | doi = 10.1097/MOH.0b013e32835d81bf | PMID = 23385615 }}</ref>
*[[Hodgkin lymphoma]] - eosinophils not malignant.


===Site specific===
====Site specific====
*[[Eosinophilic esophagitis]].
*[[Eosinophilic esophagitis]].
*[[Eosinophilic colitis]].
*[[Eosinophilic colitis]].
*[[Eosinophilic gastritis]].
*[[Eosinophilic cholecystitis]].
*[[Pulmonary Langerhans cell histiocytosis]].
*[[Pulmonary Langerhans cell histiocytosis]].
*[[Angiolymphoid hyperplasia with eosinophilia]] (ALHE) - skin.
*[[Angiolymphoid hyperplasia with eosinophilia]] (ALHE) - skin.
*[[Eosinophilic fasciitis]].
==Microscopic==
Features:
*Bilobed nucleus.
*Granular eosinophilic cytoplasm.
DDx:
*[[Paneth cell]]s - for intraepithelial eosinophils.
**Eosinophils have smaller (~1/2) more intensely red granules.
===Images===
<gallery>
Image:Eosinophilic colitis - alt -- very high mag.jpg | Eosinophils in [[eosinophilic colitis]]. (WC)
</gallery>


==See also==
==See also==
*[[Neutrophil]].
*[[Neutrophil]].
==References==
{{Reflist|2}}


[[Category:Basics]]
[[Category:Basics]]

Latest revision as of 21:02, 1 June 2023

Eosinophil is a common type of white blood cell.

General

Diseases with many eosinophils

Neoplastic related

Site specific

Microscopic

Features:

  • Bilobed nucleus.
  • Granular eosinophilic cytoplasm.

DDx:

  • Paneth cells - for intraepithelial eosinophils.
    • Eosinophils have smaller (~1/2) more intensely red granules.

Images

See also

References

  1. Podjasek, JC.; Butterfield, JH. (Apr 2013). "Mortality in hypereosinophilic syndrome: 19 years of experience at Mayo Clinic with a review of the literature.". Leuk Res 37 (4): 392-5. doi:10.1016/j.leukres.2012.12.016. PMID 23332454.
  2. Noel, P.; Mesa, RA. (Mar 2013). "Eosinophilic myeloid neoplasms.". Curr Opin Hematol 20 (2): 157-62. doi:10.1097/MOH.0b013e32835d81bf. PMID 23385615.