Cytomegalovirus colitis
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Cytomegalovirus colitis is a type of colitis.
General
- Uncommon.
- Immunosuppressed population at risk, e.g. transplant recipients, individuals with HIV.
- Typically self-limited in immunocompetent patients.[1]
Microscopic
Features:
- Enlarged nucleus - classically in endothelial cells.
DDx:
- Infectious colitis without a distinctive morphology.
- CMV colitis superimposed on inflammatory bowel disease.
Images
CMV colitis - intermed. mag. (WC/Nephron)
CMV colitis - high mag. (WC/Nephron)
www:
IHC
- CMV +ve.
- Increases the sensitivity (compared to H&E alone).[2]
Others:
- HSV-1.
- HSV-2.
- VZV.
- EBV.
See also
References
- ↑ Kim, SH.; Kim, YS.; Kim, HW.; Yoon, HE.; Kim, HK.; Kim, YO.; Yoon, SA. (Apr 2011). "A case of cytomegalovirus colitis in an immunocompetent hemodialysis patient.". Hemodial Int 15 (2): 297-300. doi:10.1111/j.1542-4758.2010.00520.x. PMID 21226839.
- ↑ Beaugerie, L.; Cywiner-Golenzer, C.; Monfort, L.; Girard, PM.; Carbonnel, F.; Ngô, Y.; Cosnes, J.; Rozenbaum, W. et al. (Apr 1997). "Definition and diagnosis of cytomegalovirus colitis in patients infected by human immunodeficiency virus.". J Acquir Immune Defic Syndr Hum Retrovirol 14 (5): 423-9. PMID 9170416.