Difference between revisions of "Cystic nephroma, adult type"
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====Case 2==== | ====Case 2==== | ||
<gallery> | |||
Image: Cystic nephroma -- low mag.jpg | CN - low mag. | |||
Image: Cystic nephroma -- intermed mag.jpg | CN - intermed. mag. | |||
Image: Cystic nephroma -- high mag.jpg | CN - high mag. | |||
Image: Cystic nephroma - alt -- high mag.jpg | CN - high mag. | |||
Image: Cystic nephroma -- very high mag.jpg | CN - very high mag. | |||
Image: Cystic nephroma - a -- low mag.jpg | CN - low mag. | |||
Image: Cystic nephroma - b -- low mag.jpg | CN - low mag. | |||
Image: Cystic nephroma - b -- intermed mag.jpg | CN - intermed. mag. | |||
Image: Cystic nephroma - b -- high mag.jpg | CN - high mag. | |||
</gallery> | |||
==IHC== | ==IHC== | ||
Revision as of 20:45, 14 May 2015
Cystic nephroma is a rare, benign kidney tumour.
Turbiner et al.[1] have suggested that cystic nephroma and mixed epithelial and stromal tumour (MEST) are one tumour; the lumping term is renal epithelial and stromal tumour (abbreviated REST).
General
- Rare.[2]
- Good prognosis/benign.[2][3]
- Considered to be on a spectrum with cystic partially differentiated nephroblastoma and Wilms tumour.[3]
Gross
- Bubble wrap-like appearance.
Image
Bubble wrap. (WC)
www:
Microscopic
Features:
- Cysts lined by simple epithelium with hobnailing - key feature.
- Stroma has an ovarian look:
- Blue (basophilic).
- Spindle cells.
Notes:
- Parenchymal elements (e.g. glomueruli, tubules) are not found in the septa between the cysts.
Images
Case 1
Cystic nephroma - low mag. (WC/Nephron)
Cystic nephroma - intermed. mag. (WC/Nephron)
Case 2
CN - low mag.
CN - intermed. mag.
CN - high mag.
CN - high mag.
CN - very high mag.
CN - low mag.
CN - low mag.
CN - intermed. mag.
CN - high mag.
IHC
Features:
- ER +ve.
- PR +ve.
- CD10 +ve.
See also
References
- ↑ Turbiner, J.; Amin, MB.; Humphrey, PA.; Srigley, JR.; De Leval, L.; Radhakrishnan, A.; Oliva, E. (Apr 2007). "Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term.". Am J Surg Pathol 31 (4): 489-500. doi:10.1097/PAS.0b013e31802bdd56. PMID 17414095.
- ↑ 2.0 2.1 2.2 Mohanty, D.; Jain, BK.; Agrawal, V.; Gupta, A. (May 2010). "Cystic nephroma: a diagnostic dilemma.". Saudi J Kidney Dis Transpl 21 (3): 518-20. PMID 20427881.
- ↑ 3.0 3.1 van den Hoek, J.; de Krijger, R.; van de Ven, K.; Lequin, M.; van den Heuvel-Eibrink, MM. (2009). "Cystic nephroma, cystic partially differentiated nephroblastoma and cystic Wilms' tumor in children: a spectrum with therapeutic dilemmas.". Urol Int 82 (1): 65-70. doi:10.1159/000176028. PMID 19172100.