Biphenotypic sinonasal sarcoma

Biphenotypic sinonasal sarcoma is a rare bland appearing malignant tumour of the head and neck.

It is also known as low grade sinonasla sarcoma with neural and myogenic features, abbreviated LGSSNMF.

General

• Rare.
• Female predominant.

Microscopic

Features;

• Bland hypercellular stroma typically without many mitoses.
• Invaginating glandular epithelium.

DDx:

• Solitary fibrous tumour.
• Schwannoma.
• hemangiopericytoma.

IHC

• Actin +ve.
• S-100 +ve (strong).

See also

• Head and neck pathology.