Difference between revisions of "Basal cell hyperplasia of the prostate"

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#redirect [[Prostate_gland#Basal_cell_hyperplasia_of_the_prostate]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Basal cell hyperplasia of prostate - very high mag.jpg
| Width      =
| Caption    = Basal cell hyperplasia of prostate. [[H&E stain]]. (WC)
| Synonyms  =
| Micro      = low power gland architecture near normal, glands usually ''not'' as small as cancer, usu. lack nuclear hyperchromasia, two cell populations (as in normal prostate glands), basal cells may have [[nucleoli]]
| Subtypes  =
| LMDDx      = urothelial metaplasia, [[prostate carcinoma]]
| Stains    =
| IHC        = basal presents (p63 +ve, CK34betaE12 +ve)
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[prostate gland]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      = none
| Symptoms  = none
| Prevalence = common
| Bloodwork  =
| Rads      = none
| Endoscopy  =
| Prognosis  = benign
| Other      = incidental microscopic finding
| ClinDDx    =
| Tx        = none
}}
'''Basal cell hyperplasia of the prostate''', also known as '''basal cell hyperplasia''', is a benign change of the [[prostate gland]] that may be misdiagnosed as [[prostate carcinoma]].
 
==General==
*Benign lesion that can be misdiagnosed as cancer.<ref name=pmid6195916>{{Cite journal  | last1 = Cleary | first1 = KR. | last2 = Choi | first2 = HY. | last3 = Ayala | first3 = AG. | title = Basal cell hyperplasia of the prostate. | journal = Am J Clin Pathol | volume = 80 | issue = 6 | pages = 850-4 | month = Dec | year = 1983 | doi =  | PMID = 6195916 }}</ref>
 
==Microscopic==
Features:<ref>URL: [http://pathologyoutlines.com/prostate.html#bch http://pathologyoutlines.com/prostate.html#bch]. Accessed on: 28 June 2010.</ref>
*Low power gland architecture near normal.<ref>URL: [http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html]. Accessed on: 28 June 2010.</ref><ref>URL: [http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html]. Accessed on: 28 June 2010.</ref>
**Glands ''not'' as small as cancer.
**Folds in gland lumina.
*No nuclear hyperchromasia.
*Two cell populations (as in normal prostate glands).
*Basal cells may have [[nucleoli]].
 
DDx:
*[[High-grade prostatic intraepithelial neoplasia]] - has nuclear hyperchromasia, architecture usually different (micropapillary, tufted, cribriform or flat).
*[[Prostatic adenocarcinoma]].
*[[Adenoid cystic/basal cell carcinoma of the prostate]] - for the adenoid cystic-like pattern of BCH.<ref name=pmid15371944>{{Cite journal  | last1 = McKenney | first1 = JK. | last2 = Amin | first2 = MB. | last3 = Srigley | first3 = JR. | last4 = Jimenez | first4 = RE. | last5 = Ro | first5 = JY. | last6 = Grignon | first6 = DJ. | last7 = Young | first7 = RH. | title = Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classification. | journal = Am J Surg Pathol | volume = 28 | issue = 10 | pages = 1289-98 | month = Oct | year = 2004 | doi =  | PMID = 15371944 }}</ref>
*Urothelial metaplasia of the prostate - larger cells, cell borders seen.
 
===Images===
<gallery>
Image: Basal cell hyperplasia of prostate - intermed mag.jpg | BCH - intermed. mag.
Image: Basal cell hyperplasia of prostate - high mag.jpg | BCH - high mag.
Image: Basal cell hyperplasia of prostate - very high mag.jpg | BCH - very high mag.
Image: Basal cell hyperplasia of prostate - alt - very high mag.jpg | BCH - very high mag.
</gallery>
====www====
*[http://webpathology.com/image.asp?case=18&n=1 Basal cell hyperplasia of the prostate (webpathology.com)].
 
==Sign out==
*Usually not reported.
 
==See also==
*[[Prostate gland]].
 
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Genitourinary pathology]]

Latest revision as of 14:16, 30 June 2016

Basal cell hyperplasia of the prostate
Diagnosis in short

Basal cell hyperplasia of prostate. H&E stain. (WC)
LM low power gland architecture near normal, glands usually not as small as cancer, usu. lack nuclear hyperchromasia, two cell populations (as in normal prostate glands), basal cells may have nucleoli
LM DDx urothelial metaplasia, prostate carcinoma
IHC basal presents (p63 +ve, CK34betaE12 +ve)
Site prostate gland
Signs none
Symptoms none
Prevalence common
Radiology none
Prognosis benign
Other incidental microscopic finding
Treatment none

Basal cell hyperplasia of the prostate, also known as basal cell hyperplasia, is a benign change of the prostate gland that may be misdiagnosed as prostate carcinoma.

General

  • Benign lesion that can be misdiagnosed as cancer.[1]

Microscopic

Features:[2]

  • Low power gland architecture near normal.[3][4]
    • Glands not as small as cancer.
    • Folds in gland lumina.
  • No nuclear hyperchromasia.
  • Two cell populations (as in normal prostate glands).
  • Basal cells may have nucleoli.

DDx:

Images

  • BCH - intermed. mag.

  • BCH - high mag.

  • BCH - very high mag.

  • BCH - very high mag.

www

Sign out

  • Usually not reported.

See also

References

  1. ↑ Cleary, KR.; Choi, HY.; Ayala, AG. (Dec 1983). "Basal cell hyperplasia of the prostate.". Am J Clin Pathol 80 (6): 850-4. PMID 6195916.
  2. ↑ URL: http://pathologyoutlines.com/prostate.html#bch. Accessed on: 28 June 2010.
  3. ↑ URL: http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html. Accessed on: 28 June 2010.
  4. ↑ URL: http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html. Accessed on: 28 June 2010.
  5. ↑ McKenney, JK.; Amin, MB.; Srigley, JR.; Jimenez, RE.; Ro, JY.; Grignon, DJ.; Young, RH. (Oct 2004). "Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classification.". Am J Surg Pathol 28 (10): 1289-98. PMID 15371944.
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