Difference between revisions of "Acquired cystic disease-associated renal cell carcinoma"

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==General==
==General==
*Arise in the context of long-standing [[end-stage renal disease]] (ESRD).<ref name=pmid23471757>{{Cite journal  | last1 = Ahn | first1 = S. | last2 = Kwon | first2 = GY. | last3 = Cho | first3 = YM. | last4 = Jun | first4 = SY. | last5 = Choi | first5 = C. | last6 = Kim | first6 = HJ. | last7 = Park | first7 = YW. | last8 = Park | first8 = WS. | last9 = Shim | first9 = JW. | title = Acquired cystic disease-associated renal cell carcinoma: further characterization of the morphologic and immunopathologic features. | journal = Med Mol Morphol | volume =  | issue =  | pages =  | month = Mar | year = 2013 | doi = 10.1007/s00795-013-0028-x | PMID = 23471757 }}</ref>
*Arise in the context of long-standing [[end-stage renal disease]] (ESRD).<ref name=pmid23471757>{{Cite journal  | last1 = Ahn | first1 = S. | last2 = Kwon | first2 = GY. | last3 = Cho | first3 = YM. | last4 = Jun | first4 = SY. | last5 = Choi | first5 = C. | last6 = Kim | first6 = HJ. | last7 = Park | first7 = YW. | last8 = Park | first8 = WS. | last9 = Shim | first9 = JW. | title = Acquired cystic disease-associated renal cell carcinoma: further characterization of the morphologic and immunopathologic features. | journal = Med Mol Morphol | volume =  | issue =  | pages =  | month = Mar | year = 2013 | doi = 10.1007/s00795-013-0028-x | PMID = 23471757 }}</ref>
==Gross==
*Cysts.


==Microscopic==
==Microscopic==

Revision as of 01:44, 12 January 2014

Acquired cystic disease-associated renal cell carcinoma, abbreviated ACD-RCC, is a rare kidney cancer that arises in the context of chronic renal failure.

General


Gross

  • Cysts.

Microscopic

Features:

  • Tubular strucutres with cribriforming.
    • Hobnail cells.
  • Oxylate crystals - important.
    • Look somewhat like cholesterol clefts.

DDx:

IHC

Features:[1]

  • AMACR +ve.
  • CD10 +ve.
  • Pankeratin +ve.
  • CK7 +ve (heterogeneous).

Others:[1]

  • CD68 -ve.
  • PAX2 -ve.

See also

References

  1. 1.0 1.1 1.2 Ahn, S.; Kwon, GY.; Cho, YM.; Jun, SY.; Choi, C.; Kim, HJ.; Park, YW.; Park, WS. et al. (Mar 2013). "Acquired cystic disease-associated renal cell carcinoma: further characterization of the morphologic and immunopathologic features.". Med Mol Morphol. doi:10.1007/s00795-013-0028-x. PMID 23471757.