Acquired cystic disease of the kidney
(Redirected from Acquired cystic renal disease)
Jump to navigation
Jump to search
Acquired cystic disease of the kidney (abbreviated ACDK), also acquired cystic disease, is a benign change of the kidney seen in chronic renal failure.
Acquired renal cystic disease and acquired cystic renal disease redirect here.
General
- Thought to arise due to uremia,[1] not specific to the type of renal dialysis, i.e. hemodialysis vs. peritoneal dialysis.
- Presence of cysts dependent on duration of dialysis:[1]
- < 3 years ~44%.
- >4 years ~80%.
- >10 years ~90%.
- Associated with renal cell carcinoma - specifically acquired cystic disease-associated renal cell carcinoma.[2]
Microscopic
Features:[3]
- Cysts - location: cortex and medulla.
- Lined by simple flattened epithelium.
DDx:
- Autosomal dominant polycystic kidney disease rarely,[3] see Microscopic in ADPKD.
- Acquired cystic disease-associated renal cell carcinoma.
- Papillary renal cell carcinoma.
See also
References
- ↑ 1.0 1.1 Fick GM, Gabow PA (October 1994). "Hereditary and acquired cystic disease of the kidney". Kidney Int. 46 (4): 951–64. PMID 7861721. http://www.nature.com/ki/journal/v46/n4/pdf/ki1994354a.pdf.
- ↑ Tickoo, SK.; dePeralta-Venturina, MN.; Harik, LR.; Worcester, HD.; Salama, ME.; Young, AN.; Moch, H.; Amin, MB. (Feb 2006). "Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia.". Am J Surg Pathol 30 (2): 141-53. PMID 16434887.
- ↑ 3.0 3.1 Kessler M, Testevuide P, Aymard B, Huu TC (1991). "Acquired renal cystic disease mimicking adult polycystic kidney disease in a patient undergoing long-term hemodialysis". Am. J. Nephrol. 11 (6): 513–7. PMID 1819219.