Eosinophil
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Eosinophil is a common type of white blood cell.
General
Diseases with many eosinophils
- Infection - esp. fungal.
- Drug reaction.
- Inflammatory fibroid polyp.
- Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome).
- Asthma.
- Kimura disease.
- Inflammatory bowel disease.
- Langerhans cell histiocytosis.
- Hypereosinophilic syndrome (HES).[1]
- Eosinophilic myeloproliferative neoplasm.[2]
- Hodgkin lymphoma - eosinophils not malignant.
Site specific
- Eosinophilic esophagitis.
- Eosinophilic colitis.
- Eosinophilic gastritis.
- Eosinophilic cholecystitis.
- Pulmonary Langerhans cell histiocytosis.
- Angiolymphoid hyperplasia with eosinophilia (ALHE) - skin.
- Eosinophilic fasciitis.
Microscopic
Features:
- Bilobed nucleus.
- Granular eosinophilic cytoplasm.
DDx:
- Paneth cells - for intraepithelial eosinophils.
- Eosinophils have smaller (~1/2) more intensely red granules.
Images
Eosinophils in eosinophilic colitis. (WC)
See also
References
- ↑ Podjasek, JC.; Butterfield, JH. (Apr 2013). "Mortality in hypereosinophilic syndrome: 19 years of experience at Mayo Clinic with a review of the literature.". Leuk Res 37 (4): 392-5. doi:10.1016/j.leukres.2012.12.016. PMID 23332454.
- ↑ Noel, P.; Mesa, RA. (Mar 2013). "Eosinophilic myeloid neoplasms.". Curr Opin Hematol 20 (2): 157-62. doi:10.1097/MOH.0b013e32835d81bf. PMID 23385615.