Cystic tumour of the atrioventricular nodal region
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| Cystic tumour of the atrioventricular nodal region | |
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| Diagnosis in short | |
 Cystic tumour of the atrioventricular nodal region. H&E stain. | |
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| Synonyms | cystic tumour of the atrioventricular node |
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| LM | cystic spaces lined by single layer of bland epithelial cells, +/-focal mononuclear inflammation, +/-psammoma bodies |
| LM DDx | cystic metastatic carcinoma |
| IHC | CEA +ve, EMA +ve |
| Gross | very small cysts in region of AV node |
| Grossing notes | see conducting system of heart |
| Site | heart - see cardiac tumours |
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| Clinical history | sudden cardiac death |
| Prevalence | very rare |
| Prognosis | good if caught in time |
| Treatment | excision |
Cystic tumour of the atrioventricular nodal region, abbreviated CTAVNR, is a rare cardiac tumour that can lead to sudden cardiac death.
It is also known as cystic tumour of the atrioventricular node.
Benign mesothelioma of the atrioventricular node is also used; however, these tumours are not mesotheliomas.[1][2]
General
- Super rare.[3]
- May cause sudden cardiac death.[4]
- Antemortem diagnosis in case reports; only four reported in literature as of 2010.[2]
Clinical:
- Conduction abnormalities.
- Complete heart block.
- Usually women.
Gross
- "Bump" in the triangle of Koch.
- Usually 1-2 mm.
- Cystic spaces.
Microscopic
Features:[4]
- Cystic spaces lined with single layer of epithelial cells.
- +/-Focal mononuclear inflammation.
- +/-Psammoma bodies.
DDx:
- Cystic metastatic carcinoma.
Images
CTAVNR - very low mag. (WC)
CTAVNR - high mag. (WC)
IHC
Features:[1]
See also
References
- ↑ 1.0 1.1 Evans, CA.; Suvarna, SK. (Nov 2005). "Cystic atrioventricular node tumour: not a mesothelioma.". J Clin Pathol 58 (11): 1232. PMID 16254122.
- ↑ 2.0 2.1 Sharma, G.; Linden, MD.; Schultz, DS.; Inamdar, KV.. "Cystic tumor of the atrioventricular node: an unexpected finding in an explanted heart.". Cardiovasc Pathol 19 (3): e75-8. doi:10.1016/j.carpath.2008.10.011. PMID 19144541.
- ↑ Kaminishi, Y.; Watanabe, Y.; Nakata, H.; Shimokama, T.; Jikuya, T. (Jan 2002). "Cystic tumor of the atrioventricular nodal region.". Jpn J Thorac Cardiovasc Surg 50 (1): 37-9. PMID 11855098.
- ↑ 4.0 4.1 Paniagua, JR.; Sadaba, JR.; Davidson, LA.; Munsch, CM. (Apr 2000). "Cystic tumour of the atrioventricular nodal region: report of a case successfully treated with surgery.". Heart 83 (4): E6. PMID 10722558.