Squamous dysplasia of the head and neck

Squamous dysplasia of the head and neck, often squamous dysplasia, is a precursor to head and neck squamous cell carcinoma.

General

• Similar to squamous dysplasia elsewhere.
• Precursor to head and neck squamous cell carcinoma.

Gross

Features:

• Erythroplakia.
• Leukoplakia.

Microscopic

Features:

• Basal nuclear atypia - may be mild.
• Lack of maturation to the surface.
• +/-Parakeratosis.

DDx:

• Squamous hyperplasia.
• Benign leukoplakia.
• Head and neck squamous cell carcinoma.

Images

www:

• Squamous dysplasia - WHO grading system (nih.gov).
• Squamous dysplasia (nih.gov).

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PHARYNGEAL WALL, POSTERIOR, BIOPSY:
- SQUAMOUS MUCOSA WITH MILD SQUAMOUS DYSPLASIA.
- NEGATIVE FOR MALIGNANCY.

See also

• Head and neck pathology.