653
edits
Difference between revisions of "Invasive breast cancer"
Jump to navigation
Jump to search
→Microscopic
| Line 505: | Line 505: | ||
**Abnormal architecture - including cribriform, solid, micropapillary, papillary. | **Abnormal architecture - including cribriform, solid, micropapillary, papillary. | ||
Photos: | |||
<gallery> | <gallery> | ||
Image:Breast Carcinoma Papillary Intracystic SolidVariant LP CTR.jpg|Breast - Papillary Intracystic Carcinoma, Solid Variant - low power (SKB) | Image:Breast Carcinoma Papillary Intracystic SolidVariant LP CTR.jpg|Breast - Papillary Intracystic Carcinoma, Solid Variant - low power (SKB) | ||
| Line 513: | Line 514: | ||
Image:Breast EncystedPapillaryCarcinoma InfiltratingDuctalCarcinoma PA.JPG|thumb|Breast - Intracystic papillary adenocarcinoma with associated invasive ductal carcinoma (SKB) | Image:Breast EncystedPapillaryCarcinoma InfiltratingDuctalCarcinoma PA.JPG|thumb|Breast - Intracystic papillary adenocarcinoma with associated invasive ductal carcinoma (SKB) | ||
</gallery> | </gallery> | ||
WebPathology<http://www.webpathology.com/images/noimage.gif> | |||
WebPathology<http://www.webpathology.com/images/noimage.gif> | |||
WebPathology<http://www.webpathology.com/images/noimage.gif> | |||
DDx<ref>{{Cite journal | last1 = Collins | first1 = LC. | last2 = Schnitt | first2 = SJ. | title = Papillary lesions of the breast: selected diagnostic and management issues. | journal = Histopathology | volume = 52 | issue = 1 | pages = 20-9 | month = Jan | year = 2008 | doi = 10.1111/j.1365-2559.2007.02898.x | PMID = 18171414 }} | DDx<ref>{{Cite journal | last1 = Collins | first1 = LC. | last2 = Schnitt | first2 = SJ. | title = Papillary lesions of the breast: selected diagnostic and management issues. | journal = Histopathology | volume = 52 | issue = 1 | pages = 20-9 | month = Jan | year = 2008 | doi = 10.1111/j.1365-2559.2007.02898.x | PMID = 18171414 }} | ||
| Line 520: | Line 524: | ||
**Is there a single cell or dual cell population in the lesion? | **Is there a single cell or dual cell population in the lesion? | ||
***ER staining will be heterologous in a benign lesion. | ***ER staining will be heterologous in a benign lesion. | ||
*** | ***Myoepithelial markers (calponin/p63/SMA +ve)s hould be positive in a benign lesion. | ||
*[[Papillary ductal carcinoma in situ]] | *[[Papillary ductal carcinoma in situ]] | ||
**Papillary DCIS shows myoepithelial cells (calponin/p63/SMA +ve) at the periphery of the involved spaces | **Papillary DCIS shows myoepithelial cells (calponin/p63/SMA +ve) at the periphery of the involved spaces | ||
**But papillary DCIS should be negative for myoepithelial cells within the focus of DCIS | |||
**Papillary intracystic carcinoma does not show myoepithelial cells at the periphery of the involved spaces | **Papillary intracystic carcinoma does not show myoepithelial cells at the periphery of the involved spaces | ||
*Invasive carcinoma arising in association with papillary intracystic carcinoma | *Invasive carcinoma arising in association with papillary intracystic carcinoma | ||