Difference between revisions of "Diffuse lung diseases"

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997 bytes removed ,  04:09, 31 May 2014
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==Non-specific interstitial pneumonia==
==Non-specific interstitial pneumonia==
*Abbreviated ''NSIP''.
*Abbreviated ''NSIP''.
 
{{Main|Non-specific interstitial pneumonia}}
===General===
*Better prognosis than [[UIP]].
*Some radiologists and pathologists don't believe in this entity.
 
Associations:<ref name=Ref_WMSP92>{{Ref WMSP|92}}</ref>
*Connective tissue disease.
*[[Rheumatoid arthritis]].
 
===Gross/Radiology===
*No honeycombing.
*Fibrosis usually lower lung zone.
*Patchy ground glass.
 
===Microscopic===
Features:<ref name=Ref_WMSP92>{{Ref WMSP|92}}</ref>
*Diffuse fibrosis:
**Uniform fibrosis (unlike [[UIP]]).
**"Linear fibrosis" has a good prognosis - should be mentioned in the report.
***''Linear fibrosis'' = fibrosis that follows alveolar walls + no architectural distortion.
*+/-Lymphoid nodules - association with collagen vascular disease. (???)
*+/-Focal [[organizing pneumonia]].
 
Notes:
*Inflammation in NSIP usually more prominent than in UIP.
*No honeycombing - key difference between UIP and NSIP.
 
DDx:
*Collagen vascular disease.
*Drug reaction.
*[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis).
*[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation.


==Organizing pneumonia==
==Organizing pneumonia==
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