|
|
Line 112: |
Line 112: |
| ==Non-specific interstitial pneumonia== | | ==Non-specific interstitial pneumonia== |
| *Abbreviated ''NSIP''. | | *Abbreviated ''NSIP''. |
| | | {{Main|Non-specific interstitial pneumonia}} |
| ===General===
| |
| *Better prognosis than [[UIP]].
| |
| *Some radiologists and pathologists don't believe in this entity.
| |
| | |
| Associations:<ref name=Ref_WMSP92>{{Ref WMSP|92}}</ref>
| |
| *Connective tissue disease.
| |
| *[[Rheumatoid arthritis]].
| |
| | |
| ===Gross/Radiology===
| |
| *No honeycombing.
| |
| *Fibrosis usually lower lung zone.
| |
| *Patchy ground glass.
| |
| | |
| ===Microscopic===
| |
| Features:<ref name=Ref_WMSP92>{{Ref WMSP|92}}</ref>
| |
| *Diffuse fibrosis:
| |
| **Uniform fibrosis (unlike [[UIP]]).
| |
| **"Linear fibrosis" has a good prognosis - should be mentioned in the report.
| |
| ***''Linear fibrosis'' = fibrosis that follows alveolar walls + no architectural distortion.
| |
| *+/-Lymphoid nodules - association with collagen vascular disease. (???)
| |
| *+/-Focal [[organizing pneumonia]].
| |
| | |
| Notes:
| |
| *Inflammation in NSIP usually more prominent than in UIP.
| |
| *No honeycombing - key difference between UIP and NSIP.
| |
| | |
| DDx:
| |
| *Collagen vascular disease.
| |
| *Drug reaction.
| |
| *[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis).
| |
| *[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation.
| |
|
| |
|
| ==Organizing pneumonia== | | ==Organizing pneumonia== |