Talk:Diffuse lung diseases

A. LUNG, RIGHT LOWER LOBE, WEDGE RESECTION:
- MODERATE PERIPHERAL MICROCYSTS, FOCALLY WITH CILIATED EPITHELIUM.
- PATCHY MODERATE, FOCAL SEVERE, INTERSTITIAL FIBROSIS -- PREDOMINANTLY PERIPHERAL.
- PATCHY MILD CHRONIC INTERSTITIAL INFLAMMATION AND FIBROBLASTIC FOCI.
- PULMONARY ARTERY ATHEROSCLEROTIC CHANGES, MODERATE, COMPATIBLE WITH PULMONARY
  HYPERTENSION.

B. LUNG, RIGHT MIDDLE LOBE, WEDGE RESECTION:
- PATCHY MILD CHRONIC INTERSTITIAL INFLAMMATION AND FIBROBLASTIC FOCI.
- MINIMAL INTERSTITIAL FIBROSIS.
- PULMONARY ARTERY ATHEROSCLEROTIC CHANGES, MODERATE, COMPATIBLE WITH PULMONARY
  HYPERTENSION.
- FOCAL PERIPHERAL MICROCYSTS.

C. LUNG, RIGHT UPPER LOBE, WEDGE RESECTION:
- PULMONARY ARTERY ATHEROSCLEROTIC CHANGES, MODERATE-TO-SEVERE, COMPATIBLE WITH
  PULMONARY HYPERTENSION.
- VERY FOCAL MILD INTERSTITIAL FIBROSIS, PERIPHERAL.
- FOCALLY PROMINENT AIRWAY MACROPHAGES.

COMMENT:
The findings (fibroblastic foci, peripheral fibrosis, microcyst formation, lower lobe
involvement most severe) are compatible with usual interstitial pneumonia (UIP).

The differential diagnosis includes collagen vascular diseases, chronic drug toxicity and
idiopathic pulmonary fibrosis (IPF).

A more general differential diagnosis would include asbestosis and chronic hypersenstivity
pneumonitis (CHP). The pattern is not compatible with CHP.  No ferruginous bodies are
identified to suggest asbestos and no history of asbestos exposure is provided.