Difference between revisions of "Talk:Neuropathology"

Jump to navigation Jump to search
231 bytes added ,  14:28, 17 November 2010
m
(tweak)
m (→‎CADASIL: update)
Line 10: Line 10:
==CADASIL==
==CADASIL==
===Microscopic===
===Microscopic===
The section shows normal skin with numerous small blood vessels. The blood vessels do NOT stain with the Notch-3 immunostain. The Notch-3 control has the usual staining.  
The biopsy, containing epidermis, dermis and subcutaneous tissue, is technically satisfactory. Immunostains utilizing a monoclonal antibody 1E4 (anti-Notch-3) at dilution 1:50 shows the absence of granular deposits in the walls of small arteries and veins in the dermis and subcutaneous tissue. Immunostains are strongly positive on positive control tissue from a patient known to have CADASIL.
 
===Final diagnosis===
===Final diagnosis===
SKIN, BIOPSY:
SKIN, BIOPSY:
<br> - NO PATHOLOGIC DIAGNOSIS.
<br>- ABSENCE OF NOTCH-3 IMMUNOSTAINING.
48,830

edits

Navigation menu