Informatics

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Informatics is the management of information. Pathologists, unfortunately, mostly have poor tools for this job.

Software in use at pathology departments

Information systems

Dictation

Content management

Biobanking management

  • Centraxx.

Image analysis

  • Cytomine - under an Apache license.[1][2]

Pathology wikis

Main article: Pathology wikis
  • Wiki use for the dissemination of pathology knowledge is increasing.
  • In the general sphere, Wikipedia is dominating and will probably continue to do so.[3]

Open source

Open source in pathology appears to be some way off. One opinion paper[4] addresses this issue.

The radiologists are more on the ball here, e.g. UCLA's OpenSourcePACS.[5]

A few institutions (mostly American) are coming to understand this and have formed the Open Digital Pathology Consortium (opendp.org). There is also an open slide project (openslide.org).

QPath is a open source software platform for whole slide image analysis.[6]

Cytomine is a web-based open source image processing and analysis software.

ASAP is an open-source whole-slide image viewer.

Ilastik - interactive learning and segmentation toolkit is an open source tool to perform segmentation and classification of images. Cureently it does not support full virtual slides.[7]

Whole-Slide Images

  • Most common formats:
   **Philips (.tiff)
   **Aperio (.svs, .tif)
   **Hamamatsu (.vms, .vmu, .ndpi)
   **Leica (.scn)
   **Sakura (.svslide)
   **MIRAX (.mrxs)
   **Ventana (.bif, .tif)
   **Generic tiled TIFF (.tif)

SlideJ is a plugin for ImageJ for viewing most of the above mentioned formats.[8]

  • There is a push for an open virtual slide format.
  • A free C library exists to read whole-slide images.[9]

Health informatics directory

  • The University of Freiburg put together a list in 2010.[10]

See also

References

  1. ↑ URL: http://www.cytomine.be/. Accessed on: 20 April 2016.
  2. ↑ Marée, R.; Rollus, L.; Stévens, B.; Hoyoux, R.; Louppe, G.; Vandaele, R.; Begon, JM.; Kainz, P. et al. (Jan 2016). "Collaborative analysis of multi-gigapixel imaging data using Cytomine.". Bioinformatics. doi:10.1093/bioinformatics/btw013. PMID 26755625.
  3. ↑ Heilman, JM.; Kemmann, E.; Bonert, M.; Chatterjee, A.; Ragar, B.; Beards, GM.; Iberri, DJ.; Harvey, M. et al. (2011). "Wikipedia: a key tool for global public health promotion.". J Med Internet Res 13 (1): e14. doi:10.2196/jmir.1589. PMID 21282098.
  4. ↑ Rubin A (December 2004). "An open pathology computer system". J. Clin. Pathol. 57 (12): 1252–3. doi:10.1136/jcp.2004.020826. PMC 1770514. PMID 15563662. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770514/.
  5. ↑ Bui, AA.; Morioka, C.; Dionisio, JD.; Johnson, DB.; Sinha, U.; Ardekani, S.; Taira, RK.; Aberle, DR. et al. (Jan 2007). "OpenSourcePACS: an extensible infrastructure for medical image management.". IEEE Trans Inf Technol Biomed 11 (1): 94-109. PMID 17249408.
  6. ↑ Bankhead, P.; Loughrey, MB.; Fernández, JA.; Dombrowski, Y.; McArt, DG.; Dunne, PD.; McQuaid, S.; Gray, RT. et al. (12 2017). "QuPath: Open source software for digital pathology image analysis.". Sci Rep 7 (1): 16878. doi:10.1038/s41598-017-17204-5. PMID 29203879.
  7. ↑ Berg, S.; Kutra, D.; Kroeger, T.; Straehle, CN.; Kausler, BX.; Haubold, C.; Schiegg, M.; Ales, J. et al. (Sep 2019). "ilastik: interactive machine learning for (bio)image analysis.". Nat Methods. doi:10.1038/s41592-019-0582-9. PMID 31570887.
  8. ↑ Della Mea, V.; Baroni, GL.; Pilutti, D.; Di Loreto, C. (2017). "SlideJ: An ImageJ plugin for automated processing of whole slide images.". PLoS One 12 (7): e0180540. doi:10.1371/journal.pone.0180540. PMID 28683129.
  9. ↑ URL: http://openslide.org/. Accessed on: 3 May 2013.
  10. ↑ URL: [http://hiww.org/ca.html http://hiww.org/ca.html]. Accessed on: November 8, 2014.

External links

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