Giant cell lesions
Giant cell lesions appear from time to time.
The DDx is large:[1]
- True neoplasms:
- Giant cell tumour of bone.
- Giant cell tumour of soft tissue (peripheral giant cell granuloma). (???)
- Giant cell tumour of the jaw (central giant cell granuloma). (???)
- Giant cell tumour of the tendon sheath.
- Undifferentiated pleomorphic sarcoma with giant cells.
- Osteosarcoma with giant cells.
- Aneurysmal bone cyst
- Giant cell reparative granuloma (AKA solid aneurysmal bone cyst[2]).
- Non-neoplastic:
- Granulomatous disease:
- Sarcoidosis.
- Other granulomatous disease.
- Foreign body giant cells.
See also
- Bone.
- Giant cells.
- GCT - an abbreviation used for giant cell tumour and other tumours.
- Nuclear pleomorphism.
References
- ↑ Salzer-Kuntschik M (1998). "[Differential diagnosis of giant cell tumor of bone]" (in German). Verh Dtsch Ges Pathol 82: 154–9. PMID 10095427.
- ↑ Pan, Z.; Sanger, WG.; Bridge, JA.; Hunter, WJ.; Siegal, GP.; Wei, S. (Jan 2012). "A novel t(6;13)(q15;q34) translocation in a giant cell reparative granuloma (solid aneurysmal bone cyst).". Hum Pathol. doi:10.1016/j.humpath.2011.10.003. PMID 22285042.