Eosinophil

Eosinophil is a common type of white blood cell.

General

Disease with many eosinophils

• Infection - esp. fungal.
• Drug reaction.
• Inflammatory fibroid polyp.
• Churg-Strauss syndrome.
• Asthma.
• Kimura disease.
• Inflammatory bowel disease.
• Langerhans cell histiocytosis.
• Idiopathic hypereosinophilic syndrome.

Neoplastic related

• Eosinophilic myeloproliferative neoplasm.
• Hodgkin lymphoma - eosinophils not malignant.

Site specific

• Eosinophilic esophagitis.
• Eosinophilic colitis.
• Eosinophilic gastritis.
• Pulmonary Langerhans cell histiocytosis.
• Angiolymphoid hyperplasia with eosinophilia (ALHE) - skin.

Microscopic

Features:

• Bilobed nucleus.
• Granular eosinophilic cytoplasm.

DDx:

• Paneth cells.

Images

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  Eosinophils in eosinophilic colitis. (WC)

See also

• Neutrophil.