Serous carcinoma

Serous carcinoma is an epithelial malignancy that can arise from numerous sites:

• Serous carcinoma of the ovary.
• Serous carcinoma of the uterine tube.
• Serous carcinoma of the endometrium.
• Serous carcinoma of the cervix.
• Primary peritoneal serous carcinoma.

Primary peritoneal serous carcinoma

General

• Very rare.

Microscopic

Features:

• Like serous carcinoma elsewhere - see ovarian serous carcinoma.

Note:

• To exclude ovarian serous carcinoma all of the following criteria must be met:
  1. Histology of the tumour = serous carcinoma.
  2. Bulk of the tumour involves the peritoneum.
  3. Ovarian substance tumour extent less than 5 x 5 mm in plane of section.
  4. Previous ovarian serous carcinoma is excluded.
     • Old oopherectomies reviewed if possible.

IHC

• Like serous carcinoma elsewhere - see ovarian serous carcinoma.

See also

• Gynecologic pathology
• Serous carcinoma (cytology).
• Mesothelial cytopathology.