Peritoneum
(Redirected from Primary peritoneal serous carcinoma)
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The peritoneum is a much neglected area, with relatively little pathology. It includes the omentum which is dealt with in the omentum article.
Benign
Peritoneal implants
Main article: Peritoneal implants
- These are dealt with in the ovarian tumours article. Broadly speaking they may be: (1) desmoplastic non-invasive, (2) epithelial non-invasive, and (3) invasive.
Well-differentiated papillary mesothelioma
- Should not be confused with malignant mesothelioma or benign multicystic mesothelioma.
- AKA benign papillary mesothelioma.
Main article: Well-differentiated papillary mesothelioma
Peritoneal inclusion cyst
Main article: Peritoneal inclusion cyst
- AKA inflammatory cyst of the peritoneum.
- AKA mesothelial inclusion cyst.[citation needed]
- AKA benign multicystic mesothelioma.[1]
- Should not be confused with malignant mesothelioma and benign papillary mesothelioma.
Malignant
Primary peritoneal serous carcinoma
General
- Very rare.
- Reported in men.[2]
Microscopic
Features:
- Like serous carcinoma elsewhere - see ovarian serous carcinoma.
- To exclude ovarian serous carcinoma all of the following criteria must be met:[3]
- Histology of the tumour = serous carcinoma.
- Bulk of the tumour involves the peritoneum.
- Ovarian substance tumour extent less than 5 x 5 mm in plane of section.
- Previous ovarian serous carcinoma is excluded.
- Old oopherectomies reviewed if possible.
DDx:
- Ovarian serous carcinoma.
- Other serous carcinomas - see serous carcinoma.
- Malignant mesothelioma.
IHC
- Like serous carcinoma elsewhere - see ovarian serous carcinoma.
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Should have comment something like:
High-grade serous carcinoma of the ovary/fallopian tube/periteonum is associated with BRCA1/2 mutation in approximately 20% of patients. Referral to genetic counseling is recommended.
Malignant mesothelioma
Main article: Malignant mesothelioma
This is like the tumour found in the pleural cavity.
Peritoneal metastasis
- AKA metastatic peritoneal disease.
Main article: Metastasis
General
Common causes:
- Gastrointestinal tract, esp. colorectal carcinoma.
- Gynecologic tract.
Note:
- Peritoneal disease in the context of liver metastases in colorectal carcinoma contraindicates liver resection.[4]
Microscopic
- See metastasis.
See also
References
- ↑ Vallerie, AM.; Lerner, JP.; Wright, JD.; Baxi, LV. (May 2009). "Peritoneal inclusion cysts: a review.". Obstet Gynecol Surv 64 (5): 321-34. doi:10.1097/OGX.0b013e31819f93d4. PMID 19386139.
- ↑ Shmueli, E.; Leider-Trejo, L.; Schwartz, I.; Aderka, D.; Inbar, M. (Apr 2001). "Primary papillary serous carcinoma of the peritoneum in a man.". Ann Oncol 12 (4): 563-7. PMID 11398893.
- ↑ Roh, SY.; Hong, SH.; Ko, YH.; Kim, TH.; Lee, MA.; Shim, BY.; Byun, JH.; Woo, IS. et al. (Jun 2007). "Clinical characteristics of primary peritoneal carcinoma.". Cancer Res Treat 39 (2): 65-8. doi:10.4143/crt.2007.39.2.65. PMC 273931. PMID 19746214. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC273931/.
- ↑ Elias, D.; Rougier, P.; Mankarios, H.; Fahrat, F.; Lasser, P. (Mar 1993). "[Resectable liver metastases and synchronous extra-hepatic sites of colorectal origin. Surgical indications].". Presse Med 22 (11): 515-20. PMID 8511077.