Peritoneal inclusion cyst

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Peritoneal inclusion cyst is a relatively uncommon benign pathology of the peritoneum.[1]

It is also known as benign multicystic mesothelioma; it should not be confused with malignant mesothelioma and benign papillary mesothelioma.

It may referred to as inflammatory cyst of the peritoneum or mesothelial inclusion cyst.[citation needed]

Multilocular peritoneal inclusion cyst redirect here.


  • Usually conservative management.
  • Serum CA-125 usually low.
  • May occur in men.[2]



  • Multilocular thin-walled cysts containing serous fluid +/- blood.
    • Occasionally unilocular.
  • May be up to 15 cm.
  • Can be adherent to the ovary.



  • Thin-walled, irregular-shaped, cysts - unicystic or multicystic.
    • Mesothelial lining +/- squamous metaplasia.[5]
    • Eosinophilic fluid.





  • Calretinin +ve.
  • WT-1 +ve.

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Greater Omentum, Excision:
     - Multilocular peritoneal inclusion cyst with reactive changes.
     - Adipose tissue with necrosis.
     - NEGATIVE for malignancy.

See also


  1. 1.0 1.1 Vallerie, AM.; Lerner, JP.; Wright, JD.; Baxi, LV. (May 2009). "Peritoneal inclusion cysts: a review.". Obstet Gynecol Surv 64 (5): 321-34. doi:10.1097/OGX.0b013e31819f93d4. PMID 19386139.
  2. Cavallaro, A.; Murazio, M.; Modugno, P.; Vona, A.; Revelli, L.; Potenza, AE.; Colli, R.. "Benign multicystic mesothelioma of the peritoneum: a case report.". Chir Ital 54 (4): 569-72. PMID 12239771.
  3. McFadden, DE.; Clement, PB. (Dec 1986). "Peritoneal inclusion cysts with mural mesothelial proliferation. A clinicopathological analysis of six cases.". Am J Surg Pathol 10 (12): 844-54. PMID 3789251.
  4. Levy, AD.; Arnáiz, J.; Shaw, JC.; Sobin, LH.. "From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation.". Radiographics 28 (2): 583-607; quiz 621-2. doi:10.1148/rg.282075175. PMID 18349460.
  5. Ross, MJ.; Welch, WR.; Scully, RE. (Sep 1989). "Multilocular peritoneal inclusion cysts (so-called cystic mesotheliomas).". Cancer 64 (6): 1336-46. PMID 2766227.
  6. 6.0 6.1 Takemoto, S.; Kawano, R.; Honda, K.; Nakazono, A.; Shimamatsu, K. (2012). "Benign multicystic peritoneal mesothelioma mimicking recurrence of an ovarian borderline tumor: a case report.". J Med Case Rep 6 (1): 126. doi:10.1186/1752-1947-6-126. PMID 22583977.