Myxoid lesions

Myxoid lesions occasionally appear on the pathologist's desk. The differential diagnosis is very large, as many lesions have a myxoid variant.

Myxoid stroma

Features:

• Stroma has a pale/blue appearance.

GI tract:

• Inflammatory fibroid polyp.

Gyne:

• Myxoid liposarcoma.

Soft tissue:

• Low-grade fibromyxoid sarcoma.
• Myxoid liposarcoma.
• Spindle cell lipoma.
• Extraskeletal myxoid chondrosarcoma.
• Myxoid chondrosarcoma.
• Aggressive angiomyxoma.

Skin:

• Myxoma.
• Myxoid DFSP.
• Basal cell carcinoma.
• Myxoid neurofibroma.

Breast:

• Phyllodes tumour.
• Fibroadenoma.
• Myxoid fibroadenoma.

Kidney: Renomedullary interstitial cell tumour.

Salivary gland:

• Pleomorphic adenoma.

Heart:

• Atrial myxoma.

Neuropathology:

• Pilomyxoid astrocytoma.
• Myxopapillary ependymoma.
• Chordoma.
• Chordoid meningioma.

Chondromyxoid stroma

Features:

• Cells in pseudonests.
• Surrounding stroma bluish.

Salivary gland:

• Pleomorphic adenoma.

Skin:

• Chondroid syringoma.

See also

• Long power list.