Difference between revisions of "TFE3"
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{{ Infobox immunostain | |||
| Name = {{PAGENAME}} | |||
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| Use = screen to detect TFE3 rearrangements | |||
| Subspecial = [[urologic pathology]], [[soft tissue pathology]] | |||
| Pattern = nuclear stain | |||
| Positive = [[Xp11.2 translocation carcinoma]], [[alveolar soft part sarcoma]] | |||
| Negative = normal tissues | |||
| Other = | |||
}} | |||
'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]]. | '''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]]. | ||
Revision as of 15:16, 11 September 2017
| TFE3 | |
|---|---|
| Immunostain in short | |
| Use | screen to detect TFE3 rearrangements |
| Subspeciality | urologic pathology, soft tissue pathology |
| Normal staining pattern | nuclear stain |
| Positive | Xp11.2 translocation carcinoma, alveolar soft part sarcoma |
| Negative | normal tissues |
TFE3 is an immunostain used in uropathology and soft tissue pathology.
Negative
- Normal tissue.[1]
- Staining in normal tissue described as "extremely rare" - negative in adrenal gland, breast, colon, gallbaldder, lymph node, liver, prostate and skin.[2]
Positive
See also
References
- ↑ URL: http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf. Accessed on: September 11, 2017.
- ↑ Argani, P.; Lal, P.; Hutchinson, B.; Lui, MY.; Reuter, VE.; Ladanyi, M. (Jun 2003). "Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay.". Am J Surg Pathol 27 (6): 750-61. PMID 12766578.