Difference between revisions of "Adenoid cystic carcinoma of the breast"

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'''Adenoid cystic carcinoma of the breast''' is a rare type of [[breast cancer]] that is similar to a relatively common tumour of the [[salivary gland]].
'''Adenoid cystic carcinoma of the breast''' is a rare type of [[breast cancer]] that is similar to a relatively common tumour of the [[salivary gland]].
It is also known as '''breast adenoid cystic carcinoma''', abbreviated '''BACC'''.<ref name=pmid16203286>{{Cite journal  | last1 = Crisi | first1 = GM. | last2 = Marconi | first2 = SA. | last3 = Makari-Judson | first3 = G. | last4 = Goulart | first4 = RA. | title = Expression of c-kit in adenoid cystic carcinoma of the breast. | journal = Am J Clin Pathol | volume = 124 | issue = 5 | pages = 733-9 | month = Nov | year = 2005 | doi = 10.1309/61MV-ENEK-5EJ7-JKGF | PMID = 16203286 }}</ref>


==General==
==General==

Revision as of 08:06, 14 April 2015

Adenoid cystic carcinoma of the breast
Diagnosis in short

Adenoid cystic carcinoma of the breast. H&E stain.
LM DDx cribriform DCIS, invasive cribriform carcinoma, collagenous spherulosis
Site breast - see invasive breast cancer
Prevalence very rare
Prognosis good
Treatment surgery

Adenoid cystic carcinoma of the breast is a rare type of breast cancer that is similar to a relatively common tumour of the salivary gland.

It is also known as breast adenoid cystic carcinoma, abbreviated BACC.[1]

General

Microscopic

See: Adenoid cystic carcinoma article.

DDx:

Images

  • Breast Adenoid Cystic Carcinoma - low power (SKB)

  • Breast Adenoid Cystic Carcinoma - medium power (SKB)

  • Breast Adenoid Cystic Carcinoma - medium power (SKB)

  • Breast Adenoid Cystic Carcinoma - medium power (SKB)

  • Breast Adenoid Cystic Carcinoma - medium power (SKB)

  • Breast Adenoid Cystic Carcinoma - medium power (SKB)

  • Breast Adenoid Cystic Carcinoma - medium power (SKB)

  • Breast Adenoid Cystic Carcinoma - high power (SKB)

  • Breast Adenoid Cystic Carcinoma - high power (SKB)

  • Breast Adenoid Cystic Carcinoma - high power (SKB)

  • Breast Adenoid Cystic Carcinoma - high power (SKB)

  • Breast - Adenoid Cystic Carcinoma - Solid Type - Low power (SKB)

  • Breast - Adenoid Cystic Carcinoma - Solid Type - medium power - Aggregates of basaloid cells without tubule or cyst formation. (SKB)

  • Breast - Adenoid Cystic Carcinoma - Solid Type - High power (SKB)

  • Breast Adenoid Cystic Carcinoma - Solid Type - high power (SKB)

www:

IHC

  • One of the 'good prognosis' triple negative breast cancers - ER, PR and HER2 negative.[3]
  • Basal-like breast cancer - p63 and CK5/6 positive.[3]

CD117 positive[3]

Other Resources

Pathology Outlines [1]

See also

References

  1. ↑ Crisi, GM.; Marconi, SA.; Makari-Judson, G.; Goulart, RA. (Nov 2005). "Expression of c-kit in adenoid cystic carcinoma of the breast.". Am J Clin Pathol 124 (5): 733-9. doi:10.1309/61MV-ENEK-5EJ7-JKGF. PMID 16203286.
  2. ↑ 2.0 2.1 Boujelbene, N.; Khabir, A.; Boujelbene, N.; Jeanneret Sozzi, W.; Mirimanoff, RO.; Khanfir, K. (Dec 2011). "Clinical review - Breast adenoid cystic carcinoma.". Breast. doi:10.1016/j.breast.2011.11.006. PMID 22154460.
  3. ↑ 3.0 3.1 3.2 Azoulay, S.; Laé, M.; Fréneaux, P.; Merle, S.; Al Ghuzlan, A.; Chnecker, C.; Rosty, C.; Klijanienko, J. et al. (Dec 2005). "KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome.". Mod Pathol 18 (12): 1623-31. doi:10.1038/modpathol.3800483. PMID 16258515.
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