Difference between revisions of "Testicular scar"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
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| Caption = | |||
| Synonyms = scar of testis | |||
| Micro = seminiferous tubules replaced by fibrosis (hyaline material with a relatively low cellularity and no nuclear atypia) +/-hemosiderin-laden macrophages, atrophic changes (see ''[[testicular atrophy]]'') | |||
| Subtypes = | |||
| LMDDx = necrotic tumour, (residual) testicular tumour (e.g. [[germ cell tumour]]) | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = tan brown or white, well-circumscribed | |||
| Grossing = | |||
| Site = [[testis]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = +/-history of testicular tumour | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = unremarkable | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = (residual) testicular tumour | |||
| Tx = | |||
}} | |||
'''Testicular scar''', also '''scar of testis''', is a phenomenon that may arise in the context of treatment for a [[germ cell tumour]]<ref>{{cite journal |author=Ramsey S, Kerr G, Howard GC, Donat R |title=Orchidectomy after primary chemotherapy for metastatic testicular cancer |journal=Urol. Int. |volume=91 |issue=4 |pages=439–44 |year=2013 |pmid=24021555 |doi=10.1159/000350858 |url=}}</ref> or result from the spontaneous regression of a (germ cell) tumour.<ref name=pmid16819328>{{cite journal |author=Balzer BL, Ulbright TM |title=Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases |journal=Am. J. Surg. Pathol. |volume=30 |issue=7 |pages=858–65 |year=2006 |month=July |pmid=16819328 |doi=10.1097/01.pas.0000209831.24230.56 |url=}}</ref> | '''Testicular scar''', also '''scar of testis''', is a phenomenon that may arise in the context of treatment for a [[germ cell tumour]]<ref>{{cite journal |author=Ramsey S, Kerr G, Howard GC, Donat R |title=Orchidectomy after primary chemotherapy for metastatic testicular cancer |journal=Urol. Int. |volume=91 |issue=4 |pages=439–44 |year=2013 |pmid=24021555 |doi=10.1159/000350858 |url=}}</ref> or result from the spontaneous regression of a (germ cell) tumour.<ref name=pmid16819328>{{cite journal |author=Balzer BL, Ulbright TM |title=Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases |journal=Am. J. Surg. Pathol. |volume=30 |issue=7 |pages=858–65 |year=2006 |month=July |pmid=16819328 |doi=10.1097/01.pas.0000209831.24230.56 |url=}}</ref> | ||
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==Gross== | ==Gross== | ||
*Tan-brown or white lesion. | *Tan-brown or white lesion. | ||
*Well-circumscribed. | |||
==Microscopic== | ==Microscopic== | ||
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DDx: | DDx: | ||
*Necrotic tumour. | *[[necrosis|Necrotic]] tumour. | ||
*[[Germ cell tumour]], e.g. [[seminoma]]. | *[[Germ cell tumour]], e.g. [[seminoma]]. | ||
Revision as of 03:31, 27 July 2014
| Testicular scar | |
|---|---|
| Diagnosis in short | |
|
| |
| Synonyms | scar of testis |
|
| |
| LM | seminiferous tubules replaced by fibrosis (hyaline material with a relatively low cellularity and no nuclear atypia) +/-hemosiderin-laden macrophages, atrophic changes (see testicular atrophy) |
| LM DDx | necrotic tumour, (residual) testicular tumour (e.g. germ cell tumour) |
| Gross | tan brown or white, well-circumscribed |
| Site | testis |
|
| |
| Clinical history | +/-history of testicular tumour |
| Prevalence | uncommon |
| Blood work | unremarkable |
| Prognosis | benign |
| Clin. DDx | (residual) testicular tumour |
Testicular scar, also scar of testis, is a phenomenon that may arise in the context of treatment for a germ cell tumour[1] or result from the spontaneous regression of a (germ cell) tumour.[2]
General
- Well-reported uncommon finding.
Gross
- Tan-brown or white lesion.
- Well-circumscribed.
Microscopic
Features:
- Seminiferous tubules replaced by fibrosis.
- Hyaline material with a relatively low cellularity and no nuclear atypia.
- +/-Hemosiderin-laden macrophages.
- Atrophic changes[2] - see testicular atrophy.
DDx:
- Necrotic tumour.
- Germ cell tumour, e.g. seminoma.
Sign out
TESTICLE, RIGHT, ORCHIECTOMY: - TESTICULAR SCAR REPLACING MANY OF THE SEMINIFEROUS TUBULES. - REMAINING SEMINIFEROUS TUBULES WITH ATROPHIC CHANGES. - BENIGN SPERMATIC CORD AND EPIDIDYMIS. - NO EVIDENCE OF RESIDUAL GERM CELL TUMOUR. - NEGATIVE FOR MALIGNANCY.
See also
References
- ↑ Ramsey S, Kerr G, Howard GC, Donat R (2013). "Orchidectomy after primary chemotherapy for metastatic testicular cancer". Urol. Int. 91 (4): 439–44. doi:10.1159/000350858. PMID 24021555.
- ↑ 2.0 2.1 Balzer BL, Ulbright TM (July 2006). "Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases". Am. J. Surg. Pathol. 30 (7): 858–65. doi:10.1097/01.pas.0000209831.24230.56. PMID 16819328.