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Difference between revisions of "Invasive breast cancer"
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→Microscopic: more
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*If it looks like squamous cell carcinoma... in the breast it is metaplastic carcinoma. | *If it looks like squamous cell carcinoma... in the breast it is metaplastic carcinoma. | ||
Images: [http://www.breastpathology.info/Case_of_the_month/2007/COTM_0807%20discussion.html Metaplastic carcinoma (breastpathology.info)].<ref name=metaplastic>URL: [http://www.breastpathology.info/Case_of_the_month/2007/COTM_0807%20discussion.html http://www.breastpathology.info/Case_of_the_month/2007/COTM_0807%20discussion.html]. Accessed on: 28 November 2010.</ref> | |||
====Subclassification==== | |||
*There are various way to subclassify this subtype of breast cancer. | |||
**There is a series of articles on the topic by ''Wargotz & Norris'' that is quite old... yet it is mentioned in Sterberg:<ref>{{Ref Sternberg5|328}}</ref> | |||
*#Matrix-producing carcinoma.<ref>{{Cite journal | last1 = Wargotz | first1 = ES. | last2 = Norris | first2 = HJ. | title = Metaplastic carcinomas of the breast. I. Matrix-producing carcinoma. | journal = Hum Pathol | volume = 20 | issue = 7 | pages = 628-35 | month = Jul | year = 1989 | doi = | PMID = 2544506 }}</ref> | |||
*#Spindle cell carcinoma.<ref>{{Cite journal | last1 = Wargotz | first1 = ES. | last2 = Deos | first2 = PH. | last3 = Norris | first3 = HJ. | title = Metaplastic carcinomas of the breast. II. Spindle cell carcinoma. | journal = Hum Pathol | volume = 20 | issue = 8 | pages = 732-40 | month = Aug | year = 1989 | doi = | PMID = 2473024 }}</ref> | |||
*#Carcinosarcoma.<ref>{{Cite journal | last1 = Wargotz | first1 = ES. | last2 = Norris | first2 = HJ. | title = Metaplastic carcinomas of the breast. III. Carcinosarcoma. | journal = Cancer | volume = 64 | issue = 7 | pages = 1490-9 | month = Oct | year = 1989 | doi = | PMID = 2776108 }}</ref> | |||
*#Squamous cell carcinoma of ductal origin.<ref>{{Cite journal | last1 = Wargotz | first1 = ES. | last2 = Norris | first2 = HJ. | title = Metaplastic carcinomas of the breast. IV. Squamous cell carcinoma of ductal origin. | journal = Cancer | volume = 65 | issue = 2 | pages = 272-6 | month = Jan | year = 1990 | doi = | PMID = 2153044 }}</ref> | |||
*#Metaplastic carcinoma with osteoclastic giant cells.<ref>{{Cite journal | last1 = Wargotz | first1 = ES. | last2 = Norris | first2 = HJ. | title = Metaplastic carcinomas of the breast: V. Metaplastic carcinoma with osteoclastic giant cells. | journal = Hum Pathol | volume = 21 | issue = 11 | pages = 1142-50 | month = Nov | year = 1990 | doi = | PMID = 2227922 }}</ref> | |||
*The WHO subclassifies as follows:<ref>{{Ref BP|214}}</ref> | |||
*#Epithelial - includes: squamous cell carcinoma, adenocarcinoma with spindle cell differentiation, adenosquamous carcinoma. | |||
*#Mixed epithelial and mesenchymal - includes: carcinosarcoma, carcinoma with metaplasia (chondroid, osseous). | |||
===IHC=== | ===IHC=== | ||