Difference between revisions of "Forensic pathology"

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Things usually collected at autopsy:
Things usually collected at autopsy:
#Blood in EDTA tube (genetic testing).
#Blood in EDTA tube (genetic testing).
#Urine toxicology.
#Urine toxicology:
#*Useful to evaluate ''myoglobin''.
#*Useful to evaluate ''myoglobin''.
#Vitreous
#Vitreous:
#*Biochemistry (??? lytes ???).
#*Biochemistry.
#*Ketones.
#*Ketones.
#*Urea (???).
#*Urea (???).
#Bile:<ref>{{Ref HospAuto|220}}</ref>
#*Acetaminophen overdoses.
#*Opiate overdoses.


Myoglobin DDx:
Myoglobin DDx:
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*Malignant hyperthermia.
*Malignant hyperthermia.
*Serotonin syndrome.
*Serotonin syndrome.
===Biochemistry===
*Diabetes:<ref name=Ref_HospAuto221>{{Ref HospAuto|221}}</ref>
**Plasma:
***Hemoglobin A1c - increased.
***Acetone - increased.
***Beta-hydroxybutyrate - increased.
****Also increased in alcoholic ketoacidosis (though ketones low).
**Urine:
***Aceto-acetate - increased.
Death by insulin overdose:<ref name=Ref_HospAuto224>{{Ref HospAuto|224}}</ref>
*C-peptide - low.
*Insulin - high.
====Serum====
*Potassium - rises quickly and rapidly after death; completely useless.
*Sodium - tends to decrease after death; usually useless.
*Glucose - drops quickly; useless unless sky high.
*Urea, creatinine and urate - stable for ~48 hours post-mortem.<ref name=Ref_HospAuto222>{{Ref HospAuto|222}}</ref>
===Vitreous===
*Creatinine and urea - approximate those at time of death.<ref name=Ref_HospAuto222>{{Ref HospAuto|222}}</ref>


===Toxicology===
===Toxicology===