Difference between revisions of "Breast pathology"

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51 bytes added ,  02:25, 9 February 2012
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===Microscopic===
===Microscopic===
Features (fibroadenoma not otherwise specified):
Features (fibroadenoma not otherwise specified):
*Abundant [[myxoid stroma]] - most '''important feature'''.
*Abundant (intralobular) stroma - most '''important feature'''.
**Stroma is usu. white/pale on H&E -- normal stroma is pink on H&E.
**Stroma is usually white/pale, i.e. [[myxoid stroma|myxoid]], on H&E (normal stroma is pink).
***May be hyalinized (dark pink) if infarcted.
***May be hyalinized (dark pink) if infarcted.
*Compression of glandular elements -- commonly seen.
*Compression of glandular elements -- very commonly seen.


DDx:
DDx:
*Phyllodes tumour.
*[[Phyllodes tumour]].
**Stroma is more cellular than in fibroadenoma.
**Stroma is more cellular than in fibroadenoma.
**May have mitoses.
**May have mitoses.
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**Patients with phyllodes tumour are usually older than those with fibroadenoma.
**Patients with phyllodes tumour are usually older than those with fibroadenoma.
*Sarcoma.
*Sarcoma.
*[[PASH]].


Notes:
Notes:
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