Difference between revisions of "Chronic sialadenitis"
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'''Chronic sialadenitis''' is a chronic inflammatory process involving a [[salivary glands|salivary gland]]. | '''Chronic sialadenitis''' is a chronic inflammatory process involving a [[salivary glands|salivary gland]]. | ||
'''Chronic sailolithiasis''' redirects here. | '''Chronic sailolithiasis''' redirects here. '''Sialadenitis''' redirects here. | ||
''' | '''Chronic sclerosing sialadenitis''' (also known as '''Küttner tumor''') redirects here.<ref name=pmid32754389>{{cite journal |authors=Keidar E, Shermetaro J, Kwartowitz G |title=Pediatric Parotid Chronic Sclerosing Sialadenitis in an African-American Female: A Rare Case and Review of the Literature |journal=Cureus |volume=12 |issue=6 |pages=e8846 |date=June 2020 |pmid=32754389 |pmc=7386075 |doi=10.7759/cureus.8846 |url=}}</ref> | ||
==General== | ==General== | ||
Revision as of 18:27, 8 September 2020
Chronic sialadenitis is a chronic inflammatory process involving a salivary gland.
Chronic sailolithiasis redirects here. Sialadenitis redirects here. Chronic sclerosing sialadenitis (also known as Küttner tumor) redirects here.[1]
General
- Occasionally associated with malignancy, e.g. adenoid cystic carcinoma.[2]
Etiology:[3]
- Infection.
- Autoimmune (e.g. Sjögren syndrome, systemic lupus erythematosus).
- Other.
Associations:
Gross
Features:
- Typical location: submandibular salivary gland.
- Salivary gland swelling.[2]
Microscopic
Features:
- Non-neoplastic mononuclear inflammatory infiltrate (lymphocytes, plasma cells).
- Fibrosis.
- +/-Calcifications.
Note:
- If the infiltrate is predominantly lymphocytes Sjögren's is a possibility, and reporting a Focus score should be considered.
DDx:
- Lymphoma - especially MALT lymphoma.[5]
- IgG4-related sialadenitis.[6]
Image
Chronic sialadenitis. (WC/Nephron)
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SUBMANDIBULAR GLAND, RIGHT, EXCISION: - CHRONIC SIALOADENITIS. - SIALOLITHIASIS. - TWO BENIGN LYMPH NODES. - NEGATIVE FOR MALIGNANCY.
Micro
The sections show submandibular salivary gland with a mild patchy mixed mononuclear cell infiltrate, fibrosis and a large benign calcification. No zonal necrosis is identified. Significant nuclear atypia is not identified.
Alternate
The sections show a salivary gland with a patchy mixed mononuclear cell infiltrate and fibrosis. Significant nuclear atypia is not identified. Plasma cells are not prominent. Germinal centres are present.
See also
References
- ↑ Keidar E, Shermetaro J, Kwartowitz G (June 2020). "Pediatric Parotid Chronic Sclerosing Sialadenitis in an African-American Female: A Rare Case and Review of the Literature". Cureus 12 (6): e8846. doi:10.7759/cureus.8846. PMC 7386075. PMID 32754389. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386075/.
- ↑ 2.0 2.1 Hasegawa M, Cheng J, Maruyama S, et al. (June 2011). "Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background". Int J Oral Maxillofac Surg 40 (6): 647–50. doi:10.1016/j.ijom.2010.11.009. PMID 21159490.
- ↑ URL: http://emedicine.medscape.com/article/882358-overviewhttp://emedicine.medscape.com/article/882358-overview. Accessed on: 10 January 2011.
- ↑ Eliasson L, Heyden G, Landahl S, Steen B (March 1991). "Effects of tobacco and diuretics on human palatal salivary glands". J. Oral Pathol. Med. 20 (3): 126–9. PMID 2037973.
- ↑ Beasley, MJ. (Apr 2012). "Lymphoma of the Thyroid and Head and Neck.". Clin Oncol (R Coll Radiol). doi:10.1016/j.clon.2012.02.010. PMID 22475637.
- ↑ Thompson LDR (November 2019). "IgG4-Related Sialadenitis". Ear Nose Throat J: 145561319890153. doi:10.1177/0145561319890153. PMID 31760789.