Difference between revisions of "Cytomegalovirus colitis"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = enlarged nucleus - classically in endothelial cells, +/-cytoplasmic inclusions | |||
| Subtypes = | |||
| LMDDx = [[infectious colitis]] | |||
| Stains = | |||
| IHC = CMV +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[colon]] | |||
| Assdx = +/-[[HIV]] infection | |||
| Syndromes = | |||
| Clinicalhx = +/-immunosuppression, +/-immune incompetent (e.g. transplant recipients) | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Cytomegalovirus colitis''' is a type of [[colitis]]. | '''Cytomegalovirus colitis''' is a type of [[colitis]]. | ||
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*[http://www.flickr.com/photos/lunarcaustic/4615988256/ CMV colitis (flickr.com/lunar caustic)]. | *[http://www.flickr.com/photos/lunarcaustic/4615988256/ CMV colitis (flickr.com/lunar caustic)]. | ||
*[http://www.flickr.com/photos/lunarcaustic/4615988164/ CMV colitis (flickr.com/lunar caustic)] | *[http://www.flickr.com/photos/lunarcaustic/4615988164/ CMV colitis (flickr.com/lunar caustic)] | ||
*[http://alf3.urz.unibas.ch/pathopic/e/getpic-fra.cfm?id=000500 CMV colitis (unibas.ch)]. | |||
==IHC== | ==IHC== | ||
Revision as of 14:01, 8 February 2016
| Cytomegalovirus colitis | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | enlarged nucleus - classically in endothelial cells, +/-cytoplasmic inclusions |
| LM DDx | infectious colitis |
| IHC | CMV +ve |
| Site | colon |
|
| |
| Associated Dx | +/-HIV infection |
| Clinical history | +/-immunosuppression, +/-immune incompetent (e.g. transplant recipients) |
| Prevalence | rare |
Cytomegalovirus colitis is a type of colitis.
General
- Uncommon.
- Immunosuppressed population at risk, e.g. transplant recipients, individuals with HIV.
- Typically self-limited in immunocompetent patients.[1]
Microscopic
Features:
- Enlarged nucleus - classically in endothelial cells.
DDx:
- Infectious colitis without a distinctive morphology.
- CMV colitis superimposed on inflammatory bowel disease.
Images
CMV colitis - intermed. mag. (WC/Nephron)
CMV colitis - high mag. (WC/Nephron)
www:
- CMV colitis (flickr.com/lunar caustic).
- CMV colitis (flickr.com/lunar caustic)
- CMV colitis (unibas.ch).
IHC
- CMV +ve.
- Increases the sensitivity (compared to H&E alone).[2]
Others:
- HSV-1.
- HSV-2.
- VZV.
- EBV.
Images
See also
References
- ↑ Kim, SH.; Kim, YS.; Kim, HW.; Yoon, HE.; Kim, HK.; Kim, YO.; Yoon, SA. (Apr 2011). "A case of cytomegalovirus colitis in an immunocompetent hemodialysis patient.". Hemodial Int 15 (2): 297-300. doi:10.1111/j.1542-4758.2010.00520.x. PMID 21226839.
- ↑ Beaugerie, L.; Cywiner-Golenzer, C.; Monfort, L.; Girard, PM.; Carbonnel, F.; Ngô, Y.; Cosnes, J.; Rozenbaum, W. et al. (Apr 1997). "Definition and diagnosis of cytomegalovirus colitis in patients infected by human immunodeficiency virus.". J Acquir Immune Defic Syndr Hum Retrovirol 14 (5): 423-9. PMID 9170416.
- ↑ Harano, Y.; Kotajima, L.; Arioka, H. (2015). "Case of cytomegalovirus colitis in an immunocompetent patient: a rare cause of abdominal pain and diarrhea in the elderly.". Int J Gen Med 8: 97-100. doi:10.2147/IJGM.S63771. PMID 25767404.