Difference between revisions of "Invasive cribriform carcinoma of the breast"
Jump to navigation
Jump to search
(expand) |
(tweak) |
||
| Line 9: | Line 9: | ||
Features: | Features: | ||
*Cribriform architecture. | *Cribriform architecture. | ||
*[[Desmoplastic stroma]]. | |||
*+/-[[Tubular carcinoma of the breast|Tubular]] component. | |||
Note: | Note: | ||
*Cribriform component should be >90% of the tumour.<ref name=pmid23412348>{{Cite journal | last1 = Zhang | first1 = W. | last2 = Zhang | first2 = T. | last3 = Lin | first3 = Z. | last4 = Zhang | first4 = X. | last5 = Liu | first5 = F. | last6 = Wang | first6 = Y. | last7 = Liu | first7 = H. | last8 = Yang | first8 = Y. | last9 = Niu | first9 = Y. | title = Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 3 | pages = 445-57 | month = | year = 2013 | doi = | PMID = 23412348 }}</ref> | *Cribriform component should be >90% of the tumour.<ref name=pmid23412348>{{Cite journal | last1 = Zhang | first1 = W. | last2 = Zhang | first2 = T. | last3 = Lin | first3 = Z. | last4 = Zhang | first4 = X. | last5 = Liu | first5 = F. | last6 = Wang | first6 = Y. | last7 = Liu | first7 = H. | last8 = Yang | first8 = Y. | last9 = Niu | first9 = Y. | title = Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 3 | pages = 445-57 | month = | year = 2013 | doi = | PMID = 23412348 }}</ref> | ||
DDx: | DDx: | ||
| Line 24: | Line 27: | ||
Image:Breast CribriformCarcinoma HP SNP.jpg|Breast invasive cribriform carcinoma - high power. (SKB) | Image:Breast CribriformCarcinoma HP SNP.jpg|Breast invasive cribriform carcinoma - high power. (SKB) | ||
</gallery> | </gallery> | ||
www: | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563205/figure/fig01/ ICC - panels A-C (nih.gov)].<ref name=pmid23412348/> | |||
==IHC== | ==IHC== | ||
Revision as of 03:35, 20 April 2015
Invasive cribriform carcinoma of the breast is a rare type of breast cancer with a favourable prognosis.[1]
General
- Rare ~ 0.6% of breast cancer in one series.[2]
- Low grade.
- Good prognosis if pure or associated with a tubular invasive component.[3]
Microscopic
Features:
- Cribriform architecture.
- Desmoplastic stroma.
- +/-Tubular component.
Note:
- Cribriform component should be >90% of the tumour.[4]
DDx:
- Cribriform DCIS.
- Tubular carcinoma of the breast.
- Invasive ductal carcinoma of the breast with cribriform component.
Images
Breast invasive cribriform carcinoma - low power. (SKB)
Breast invasive cribriform carcinoma - medium power. (SKB)
Breast invasive cribriform carcinoma - high power. (SKB)
www:
IHC
Features:[1]
- ER +ve (9 +ve of 9 cases).
- PR +ve (9 +ve of 9 cases).
- HER2 -ve (0 +ve of 9 cases).
See also
References
- ↑ 1.0 1.1 Cong, Y.; Qiao, G.; Zou, H.; Lin, J.; Wang, X.; Li, X.; Li, Y.; Zhu, S. (Apr 2015). "Invasive cribriform carcinoma of the breast: A report of nine cases and a review of the literature.". Oncol Lett 9 (4): 1753-1758. doi:10.3892/ol.2015.2972. PMID 25789036.
- ↑ Stutz, JA.; Evans, AJ.; Pinder, S.; Ellis, IO.; Yeoman, LJ.; Wilson, AR.; Sibbering, DM. (Oct 1994). "The radiological appearances of invasive cribriform carcinoma of the breast. Nottingham Breast Team.". Clin Radiol 49 (10): 693-5. PMID 7955831.
- ↑ Page, DL.; Dixon, JM.; Anderson, TJ.; Lee, D.; Stewart, HJ. (Jul 1983). "Invasive cribriform carcinoma of the breast.". Histopathology 7 (4): 525-36. PMID 6884999.
- ↑ 4.0 4.1 Zhang, W.; Zhang, T.; Lin, Z.; Zhang, X.; Liu, F.; Wang, Y.; Liu, H.; Yang, Y. et al. (2013). "Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified.". Int J Clin Exp Pathol 6 (3): 445-57. PMID 23412348.