Difference between revisions of "Basal cell hyperplasia of the prostate"

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#redirect [[Prostate_gland#Basal_cell_hyperplasia_of_the_prostate]]
'''Basal cell hyperplasia of the prostate''', also known as '''basal cell hyperplasia''', is a benign change of the [[prostate gland]] that may be misdiagnosed as [[prostate carcinoma]].
 
==General==
*Benign lesion that can be misdiagnosed as cancer.<ref name=pmid6195916>{{Cite journal  | last1 = Cleary | first1 = KR. | last2 = Choi | first2 = HY. | last3 = Ayala | first3 = AG. | title = Basal cell hyperplasia of the prostate. | journal = Am J Clin Pathol | volume = 80 | issue = 6 | pages = 850-4 | month = Dec | year = 1983 | doi =  | PMID = 6195916 }}</ref>
 
==Microscopic==
Features:<ref>URL: [http://pathologyoutlines.com/prostate.html#bch http://pathologyoutlines.com/prostate.html#bch]. Accessed on: 28 June 2010.</ref>
*Low power gland architecture near normal.<ref>URL: [http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html]. Accessed on: 28 June 2010.</ref><ref>URL: [http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html]. Accessed on: 28 June 2010.</ref>
**Glands ''not'' as small as cancer.
**Folds in gland lumina.
*No nuclear hyperchromasia.
*Two cell populations (as in normal prostate glands).
*Basal cells may have nucleoli.
 
DDx:
*[[High-grade prostatic intraepithelial neoplasia]] - has nuclear hyperchromasia, architecture usually different (micropapillary, tufted, cribriform or flat).
*[[Prostatic adenocarcinoma]].
*[[Adenoid cystic/basal cell carcinoma of the prostate]] - for the adenoid cystic-like pattern of BCH.<ref name=pmid15371944>{{Cite journal  | last1 = McKenney | first1 = JK. | last2 = Amin | first2 = MB. | last3 = Srigley | first3 = JR. | last4 = Jimenez | first4 = RE. | last5 = Ro | first5 = JY. | last6 = Grignon | first6 = DJ. | last7 = Young | first7 = RH. | title = Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classification. | journal = Am J Surg Pathol | volume = 28 | issue = 10 | pages = 1289-98 | month = Oct | year = 2004 | doi =  | PMID = 15371944 }}</ref>
 
===Images===
<gallery>
Image: Basal cell hyperplasia of prostate - intermed mag.jpg | BCH - intermed. mag.
Image: Basal cell hyperplasia of prostate - high mag.jpg | BCH - high mag.
Image: Basal cell hyperplasia of prostate - very high mag.jpg | BCH - very high mag.
Image: Basal cell hyperplasia of prostate - alt - very high mag.jpg | BCH - very high mag.
</gallery>
====www====
*[http://webpathology.com/image.asp?case=18&n=1 Basal cell hyperplasia of the prostate (webpathology.com)].
 
==Sign out==
*Usually not reported.
 
==See also==
*[[Prostate gland]].
 
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Genitourinary pathology]]

Revision as of 02:17, 15 May 2015

Basal cell hyperplasia of the prostate, also known as basal cell hyperplasia, is a benign change of the prostate gland that may be misdiagnosed as prostate carcinoma.

General

  • Benign lesion that can be misdiagnosed as cancer.[1]

Microscopic

Features:[2]

  • Low power gland architecture near normal.[3][4]
    • Glands not as small as cancer.
    • Folds in gland lumina.
  • No nuclear hyperchromasia.
  • Two cell populations (as in normal prostate glands).
  • Basal cells may have nucleoli.

DDx:

Images

  • BCH - intermed. mag.

  • BCH - high mag.

  • BCH - very high mag.

  • BCH - very high mag.

www

Sign out

  • Usually not reported.

See also

References

  1. ↑ Cleary, KR.; Choi, HY.; Ayala, AG. (Dec 1983). "Basal cell hyperplasia of the prostate.". Am J Clin Pathol 80 (6): 850-4. PMID 6195916.
  2. ↑ URL: http://pathologyoutlines.com/prostate.html#bch. Accessed on: 28 June 2010.
  3. ↑ URL: http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f1.html. Accessed on: 28 June 2010.
  4. ↑ URL: http://www.nature.com/modpathol/journal/v16/n6/fig_tab/3880810f2.html. Accessed on: 28 June 2010.
  5. ↑ McKenney, JK.; Amin, MB.; Srigley, JR.; Jimenez, RE.; Ro, JY.; Grignon, DJ.; Young, RH. (Oct 2004). "Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classification.". Am J Surg Pathol 28 (10): 1289-98. PMID 15371944.
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