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Difference between revisions of "Microsatellite instability in colorectal cancer"
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Microsatellite instability in colorectal cancer (view source)
Revision as of 21:15, 28 December 2019
, 21:15, 28 December 2019no edit summary
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[[Image:Colorectal adenocarcinoma with MMR - MLH1 -- high mag.jpg|Loss of MLH1 staining in colorectal adenocarcinoma (left of image) and benign colorectal mucosa (right of image). (WC)]] | [[Image:Colorectal adenocarcinoma with MMR - MLH1 -- high mag.jpg|thumb|right|Loss of MLH1 staining in colorectal adenocarcinoma (left of image) and benign colorectal mucosa (right of image). (WC)]] | ||
[[Image:Tumour-infiltrating lymphocytes - 2 -- very high mag.jpg|thumb|right|[[Intratumoural lymphocytic response in colorectal carcinoma]], as may be seen in microsatellite instability. [[H&E stain]]. (WC)]] | [[Image:Tumour-infiltrating lymphocytes - 2 -- very high mag.jpg|thumb|right|[[Intratumoural lymphocytic response in colorectal carcinoma]], as may be seen in microsatellite instability. [[H&E stain]]. (WC)]] | ||
'''Microsatellite instability in colorectal cancer''', often abbreviated '''MSI''', is recognized as an important predictor of outcome in [[colorectal adenocarcinoma]], and may be seen in the context of [[Lynch syndrome]]. | '''Microsatellite instability in colorectal cancer''', often abbreviated '''MSI''', is recognized as an important predictor of outcome in [[colorectal adenocarcinoma]], and may be seen in the context of [[Lynch syndrome]]. | ||