Difference between revisions of "Invasive breast cancer"

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==Subtyping breast cancer==
==Subtyping breast cancer==
===DCIS versus LCIS===
===DCIS versus LCIS===
Stains:
Tabular comparison for DCIS versus LCIS:<ref name=Ref_BP275>{{Ref BP|275}}</ref><ref name=pmid18318578>{{cite journal |author=Yeh IT, Mies C |title=Application of immunohistochemistry to breast lesions |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=3 |pages=349-58 |year=2008 |month=March |pmid=18318578 |doi= |url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=349}}</ref>
*E-cadherin +ve DCIS, -ve LCIS.<ref name=pmid18318578>{{cite journal |author=Yeh IT, Mies C |title=Application of immunohistochemistry to breast lesions |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=3 |pages=349-58 |year=2008 |month=March |pmid=18318578 |doi= |url=http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=132&page=349}}</ref>  
{| class="wikitable sortable"
*34betaE12 +ve perinuclear LCIS, -ve DCIS.<ref name=pmid18318578/>
!Disease
*CAM5.2 peripheral stain = DCIS, perinuclear stain = LCIS.<ref name=pmid18318578/>
!E-cadherin
**CAM5.2 is against CK8.
!Beta-catenin
*Beta-catenin -ve LCIS, +ve DCIS.<ref name=pmid18318578/>
!34betaE12
!CAM5.2 (CK8)
|-
|DCIS
| +ve
| +ve
| -ve
| +ve peripheral cytoplasm
|-
|LCIS
| -ve
| -ve
| +ve perinuclear
| +ve perinuclear
|}


===Lymphovascular invasion===
===Lymphovascular invasion===
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