Difference between revisions of "Invasive breast cancer"

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=Introduction=
=Introduction=
==Types of invasive breast cancer==
==Overview of invasive breast cancer subtypes==
===Common epithelial types===
====Common epithelial subtypes====
Type and percentage of breast carcinomas:<ref name=Ref_PBoD1143>{{Ref PBoD|1143}}</ref>
Type and percentage of breast carcinomas:<ref name=Ref_PBoD1143>{{Ref PBoD|1143}}</ref>
*Ductal - [[AKA]] no special type (NST) - 79%.
*Ductal - [[AKA]] no special type (NST) - 79%.
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*Metaplastic <1%.
*Metaplastic <1%.


===Classic stromal===
===Common stromal types===
*Malignant [[phyllodes tumour]].
*[[Angiosarcoma]] - post-radiation ~ 10 years.<ref>URL: [http://www.breastpathology.info/Case_of_the_month/2007/COTM_1007%20discussion.html http://www.breastpathology.info/Case_of_the_month/2007/COTM_1007%20discussion.html]. Accessed on: 28 November 2010.</ref>
*[[Angiosarcoma]] - post-radiation ~ 10 years.<ref>URL: [http://www.breastpathology.info/Case_of_the_month/2007/COTM_1007%20discussion.html http://www.breastpathology.info/Case_of_the_month/2007/COTM_1007%20discussion.html]. Accessed on: 28 November 2010.</ref>
==Comprehensive list of invasive breast cancer subtypes==
====Epithelial====
Counterparts of in situ lesions:
*Invasive ductal carinoma, not otherwise specified.
*Invasive lobular carcinoma.
*Invasive cribriform carcinoma.
*Invasive papillary carcinoma.
*Invasive micropapillary carcinoma.
Other epithelial tumours:
*Tubular carcinoma.
*Medullary carcinoma.
*Mucinous carinoma.
*[[Metaplastic carcinoma]].
*[[Neuroendocrine tumour]].
*Apocrine carcinoma.
*Lipid-rich carcinoma.
*Secretory carcinoma.
*Oncocytic carcinoma.
*Glycogen-rich clear cell carcinoma.
Epithelial tumours seen in the [[salivary gland]]:
*[[Adenoid cystic carcinoma]].
*[[Acinic cell carcinoma]].
*Carcinoma ex pleomorphic adenoma.
Seen in the skin:
*[[Sebaceous carcinoma]].
Clinically diagnosed:
*Inflammatory carcinoma.
In situ lesions:
*[[Ductal carcinoma in situ]].
*[[Lobular carcinoma in situ]].
Proliferative lesions:
*[[Usual ductal hyperplasia]].
*[[Flat epithelial atypia]].
*[[Atypical ductal hyperplasia]].
Non-specific:
*Microinvasive carcinoma.
Papillary:
*Papilloma.
*Atypical papilloma.
*Intraductal papillary carcinoma.
Adenomas:
*Ductal adenoma.
*Tubular adenoma.
*Lactating adenoma.
*Apocrine adenoma.
*Pleomorphic adenoma.
====Myoepithelial====
*Myoepitheliosis.
*Adenomyoepithelial adenosis.
*[[Adenomyoepithelioma]].
*Malignant adenomyoepithelioma.
====Mesenchymal tumours====
:See: ''[[Soft tissue lesions]]''.
====Fibroepithelial tumours====
*[[Fibroadenoma]].
*[[Phyllodes tumour]].
*Periductal stromal sarcoma, low grade.
*Mammary hamartoma.
====Nipple lesions====
*Nipple adenoma.
*Syringomatous adenoma.
*[[Paget disease of the breast]].
====Other====
*[[Lymphoma]].
*Metastasis.


==Familial breast cancer==
==Familial breast cancer==
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=Characteristics of the subtypes=
=Characteristics of the subtypes=
===List of subtypes===
====Epithelial====
Counterparts of in situ lesions:
*Invasive ductal carinoma, not otherwise specified.
*Invasive lobular carcinoma.
*Invasive cribriform carcinoma.
*Invasive papillary carcinoma.
*Invasive micropapillary carcinoma.
Other epithelial tumours:
*Tubular carcinoma.
*Medullary carcinoma.
*Mucinous carinoma.
*[[Metaplastic carcinoma]].
*[[Neuroendocrine tumour]].
*Apocrine carcinoma.
*Lipid-rich carcinoma.
*Secretory carcinoma.
*Oncocytic carcinoma.
*Glycogen-rich clear cell carcinoma.
Epithelial tumours seen in the [[salivary gland]]:
*[[Adenoid cystic carcinoma]].
*[[Acinic cell carcinoma]].
*Carcinoma ex pleomorphic adenoma.
Seen in the skin:
*[[Sebaceous carcinoma]].
Clinically diagnosed:
*Inflammatory carcinoma.
In situ lesions:
*[[Ductal carcinoma in situ]].
*[[Lobular carcinoma in situ]].
Proliferative lesions:
*[[Usual ductal hyperplasia]].
*[[Flat epithelial atypia]].
*[[Atypical ductal hyperplasia]].
Non-specific:
*Microinvasive carcinoma.
Papillary:
*Papilloma.
*Atypical papilloma.
*Intraductal papillary carcinoma.
Adenomas:
*Ductal adenoma.
*Tubular adenoma.
*Lactating adenoma.
*Apocrine adenoma.
*Pleomorphic adenoma.
====Myoepithelial====
*Myoepitheliosis.
*Adenomyoepithelial adenosis.
*[[Adenomyoepithelioma]].
*Malignant adenomyoepithelioma.
====Mesenchymal tumours====
:See: ''[[Soft tissue lesions]]''.
====Fibroepithelial tumours====
*[[Fibroadenoma]].
*[[Phyllodes tumour]].
*Periductal stromal sarcoma, low grade.
*Mammary hamartoma.
====Nipple lesions====
*Nipple adenoma.
*Syringomatous adenoma.
*[[Paget disease of the breast]].
====Other====
*[[Lymphoma]].
*Metastasis.
==Ductal carcinoma==
==Ductal carcinoma==
*[[AKA]] "NST" = No Specific Type.
*[[AKA]] "NST" = No Specific Type.
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