Difference between revisions of "Clear cells in the kidney"
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[[Image: Benign clear cell clusters in the kidney -- intermed mag.jpg | thumb | [[Benign clear cell clusters of the kidney]] - a mimic of renal cell carcinoma. [[H&E stain]].]] | |||
[[Image: Clear cell renal cell carcinoma - 2 -- high mag.jpg | thumb | [[Clear cell renal cell carcinoma]] - the classic RCC with clear cells. [[H&E stain]].]] | |||
'''Clear cells in the kidney''' are commonly seen in [[kidney tumours|tumours]] and occasionally are seen in benign lesions. | '''Clear cells in the kidney''' are commonly seen in [[kidney tumours|tumours]] and occasionally are seen in benign lesions. | ||
''RCC with clear cells'' redirects to here. | |||
Recognized kidney tumours with clear cells or pale cytoplasm: | |||
*[[Clear cell renal cell carcinoma]]. | *[[Clear cell renal cell carcinoma]]. | ||
*[[Clear cell papillary renal cell tumour]] (previously [[clear cell papillary renal cell carcinoma]]). | *[[Clear cell papillary renal cell tumour]] (previously [[clear cell papillary renal cell carcinoma]]). | ||
*[[ELOC-mutated renal cell carcinoma]]. | *[[ELOC-mutated renal cell carcinoma]]. | ||
*[[Xp11.2 translocation carcinoma]]. | *[[Xp11.2 translocation carcinoma]]. | ||
*[[Epithelioid angiomyolipoma]].{{fact}} | |||
*[[Multilocular cystic renal neoplasm of low malignant potential]]. | |||
*[[Chromophobe renal cell carcinoma]] - not really "clear" cells. | |||
Evolving entities: | Evolving entities: | ||
*[[Melanotic Xp11 translocation renal cancer]]. | *[[Melanotic Xp11 translocation renal cancer]]. | ||
*[[Tuberous sclerosis-associated renal cell carcinoma]]. | *[[Tuberous sclerosis-associated renal cell carcinoma]]. | ||
*[[Renal cell carcinoma with fibromyomatous stroma]].<ref>{{cite journal |authors=Shah RB, Mehra R |title=Renal Cell Carcinoma Associated With TSC/MTOR Genomic Alterations: An Update on its Expanding Spectrum and an Approach to Clinicopathologic Work-up |journal=Adv Anat Pathol |volume= |issue= |pages= |date=October 2023 |pmid=37899532 |doi=10.1097/PAP.0000000000000419 |url=}}</ref><ref name=pmid36592877>{{cite journal |authors=Tjota MY, Sharma A, Wanjari P, Fitzpatrick C, Segal J, Antic T |title=TSC/MTOR mutated renal cell carcinoma with leiomyomatous stroma is a distinct entity: a comprehensive study of 12 cases |journal=Hum Pathol |volume=134 |issue= |pages=124–133 |date=April 2023 |pmid=36592877 |doi=10.1016/j.humpath.2022.12.015 |url=}}</ref> | |||
Benign things: | Benign things: | ||
*[[Benign cortical cyst of the kidney]]. | *[[Benign cortical cyst of the kidney]]. | ||
*[[Benign clear cell clusters of the kidney]]. | *[[Benign clear cell clusters of the kidney]]. | ||
*[[Adrenal gland]] cortex - biopsy of wrong anatomical site. | |||
==See also== | ==See also== | ||
| Line 21: | Line 28: | ||
*[[Clear cell carcinoma]]. | *[[Clear cell carcinoma]]. | ||
*[[Renal tumours with eosinophilic cytoplasm]]. | *[[Renal tumours with eosinophilic cytoplasm]]. | ||
==References== | |||
{{Reflist|1}} | |||
[[Category: Genitourinary pathology]] | [[Category: Genitourinary pathology]] | ||
Latest revision as of 03:27, 20 March 2024
Clear cells in the kidney are commonly seen in tumours and occasionally are seen in benign lesions.
File:Benign clear cell clusters in the kidney -- intermed mag.jpg
Benign clear cell clusters of the kidney - a mimic of renal cell carcinoma. H&E stain.
RCC with clear cells redirects to here.
Recognized kidney tumours with clear cells or pale cytoplasm:
- Clear cell renal cell carcinoma.
- Clear cell papillary renal cell tumour (previously clear cell papillary renal cell carcinoma).
- ELOC-mutated renal cell carcinoma.
- Xp11.2 translocation carcinoma.
- Epithelioid angiomyolipoma.[citation needed]
- Multilocular cystic renal neoplasm of low malignant potential.
- Chromophobe renal cell carcinoma - not really "clear" cells.
Evolving entities:
- Melanotic Xp11 translocation renal cancer.
- Tuberous sclerosis-associated renal cell carcinoma.
- Renal cell carcinoma with fibromyomatous stroma.[1][2]
Benign things:
- Benign cortical cyst of the kidney.
- Benign clear cell clusters of the kidney.
- Adrenal gland cortex - biopsy of wrong anatomical site.
See also
References
- ↑ Shah RB, Mehra R (October 2023). "Renal Cell Carcinoma Associated With TSC/MTOR Genomic Alterations: An Update on its Expanding Spectrum and an Approach to Clinicopathologic Work-up". Adv Anat Pathol. doi:10.1097/PAP.0000000000000419. PMID 37899532.
- ↑ Tjota MY, Sharma A, Wanjari P, Fitzpatrick C, Segal J, Antic T (April 2023). "TSC/MTOR mutated renal cell carcinoma with leiomyomatous stroma is a distinct entity: a comprehensive study of 12 cases". Hum Pathol 134: 124–133. doi:10.1016/j.humpath.2022.12.015. PMID 36592877.