Phyllodes tumour: Difference between revisions

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* † Stromal overgrowth = epithelial elements absent in one low power field (LPF), defined as x40;<ref name=pmid17932112>{{cite journal |author=Taira N, Takabatake D, Aogi K, ''et al'' |title=Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin |journal=Jpn. J. Clin. Oncol. |volume=37 |issue=10 |pages=730-6 |year=2007 |month=October |pmid=17932112 |doi=10.1093/jjco/hym099 |url=http://jjco.oxfordjournals.org/cgi/reprint/37/10/730}}</ref> ''LPF'' is not adequately defined - see [[LPFitis]].

* ‡ ''HPF'' is not adequately defined - see [[HPFitis]].

==IHC==

Epithelial component:

*CK7 +ve.

*ER.

*PR.

Stromal cells:<ref name=pmid14608534>{{cite journal |authors=Dunne B, Lee AH, Pinder SE, Bell JA, Ellis IO |title=An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast |journal=Hum Pathol |volume=34 |issue=10 |pages=1009–15 |date=October 2003 |pmid=14608534 |doi=10.1053/s0046-8177(03)00414-3 |url=}}</ref>

*CD34 +ve.

*BCL2 +ve.

*CK -ve.

*GATA-3 -ve.<ref name=pmid23375642>{{cite journal |authors=Cimino-Mathews A, Subhawong AP, Illei PB, Sharma R, Halushka MK, Vang R, Fetting JH, Park BH, Argani P |title=GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas |journal=Hum Pathol |volume=44 |issue=7 |pages=1341–9 |date=July 2013 |pmid=23375642 |pmc=3991123 |doi=10.1016/j.humpath.2012.11.003 |url=}}</ref>

==Sign out==

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Line 145:

<pre>

Right Breast Mass, Excision:

- ~~Phyllodes~~ tumour.

- Benign phyllodes tumour.

- NEGATIVE for malignancy.

</pre>

@@ Line 129: / Line 129: @@
 * † Stromal overgrowth = epithelial elements absent in one low power field (LPF), defined as x40;<ref name=pmid17932112>{{cite journal |author=Taira N, Takabatake D, Aogi K, ''et al'' |title=Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin |journal=Jpn. J. Clin. Oncol. |volume=37 |issue=10 |pages=730-6 |year=2007 |month=October |pmid=17932112 |doi=10.1093/jjco/hym099 |url=http://jjco.oxfordjournals.org/cgi/reprint/37/10/730}}</ref> ''LPF'' is not adequately defined - see [[LPFitis]].
 * ‡ ''HPF'' is not adequately defined - see [[HPFitis]].
+==IHC==
+Epithelial component:
+*CK7 +ve.
+*ER.
+*PR.
+Stromal cells:<ref name=pmid14608534>{{cite journal |authors=Dunne B, Lee AH, Pinder SE, Bell JA, Ellis IO |title=An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast |journal=Hum Pathol |volume=34 |issue=10 |pages=1009–15 |date=October 2003 |pmid=14608534 |doi=10.1053/s0046-8177(03)00414-3 |url=}}</ref>
+*CD34 +ve.
+*BCL2 +ve.
+*CK -ve.
+*GATA-3 -ve.<ref name=pmid23375642>{{cite journal |authors=Cimino-Mathews A, Subhawong AP, Illei PB, Sharma R, Halushka MK, Vang R, Fetting JH, Park BH, Argani P |title=GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas |journal=Hum Pathol |volume=44 |issue=7 |pages=1341–9 |date=July 2013 |pmid=23375642 |pmc=3991123 |doi=10.1016/j.humpath.2012.11.003 |url=}}</ref>
 ==Sign out==
@@ Line 134: / Line 145: @@
 <pre>
 Right Breast Mass, Excision:
-- Phyllodes tumour.
+- Benign phyllodes tumour.
 - NEGATIVE for malignancy.
 </pre>

Phyllodes tumour: Difference between revisions

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