Difference between revisions of "Anastomosing hemangioma of the kidney"
Jump to navigation
Jump to search
(fix) |
|||
(20 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
'''Anastomosing hemangioma''' a rare benign [[vascular tumour]] | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Anastomosing hemangioma of the kidney -- intermed mag.jpg | |||
| Width = | |||
| Caption = Anastomosing hemangioma of the kidney. [[H&E stain]]. | |||
| Synonyms = renal anastomosing hemangioma | |||
| Micro = vascular tumour with architecture similar to splenic sinsoids, hobnailing, +/-[[hyaline globules]], +/-[[extramedullary hematopoiesis]] | |||
| Subtypes = | |||
| LMDDx = [[angiosarcoma]], other [[hemangioma]]s, other [[vascular tumours]], [[angiomyolipoma]] | |||
| Stains = | |||
| IHC = CD34 +ve, CD31 +ve, HHV-8 | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = brown/mahogany lesion, classically centered on medulla of kidney | |||
| Grossing = [[total nephrectomy for tumour grossing]], [[partial nephrectomy grossing]] | |||
| Staging = | |||
| Site = [[kidney]] | |||
| Assdx = +/-[[end stage renal disease]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very rare | |||
| Bloodwork = | |||
| Rads = may mimic [[renal cell carcinoma]] | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[renal tumours]] | |||
| Tx = excision for definitive diagnosis? | |||
}} | |||
'''Anastomosing hemangioma of the kidney''' a rare benign [[vascular tumour]] of [[kidney]] that may mimic [[angiosarcoma]].<ref name=pmid19606014>{{Cite journal | last1 = Montgomery | first1 = E. | last2 = Epstein | first2 = JI. | title = Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma. | journal = Am J Surg Pathol | volume = 33 | issue = 9 | pages = 1364-9 | month = Sep | year = 2009 | doi = 10.1097/PAS.0b013e3181ad30a7 | PMID = 19606014 }}</ref> | |||
==General== | ==General== | ||
*Rare - case reports. | *Rare - case reports. | ||
**The bigger category ''vascular tumours of the kidney'' is rare; in the world literature (as of 2015), according to Omiyale, there are approximately 40 angiosarcoma and 220 hemangiomas.<ref name=pmid26244138>{{Cite journal | last1 = Omiyale | first1 = AO. | title = Anastomosing hemangioma of the kidney: a literature review of a rare morphological variant of hemangioma. | journal = Ann Transl Med | volume = 3 | issue = 11 | pages = 151 | month = Jul | year = 2015 | doi = 10.3978/j.issn.2305-5839.2015.06.16 | PMID = 26244138 }}</ref> | |||
*Typically seen in [[end stage renal disease]].<ref name=pmid27543862/> | |||
*May mimic renal cell carcinoma clinically.<ref name=pmid28727378>{{Cite journal | last1 = Silva | first1 = MA. | last2 = Fonseca | first2 = EKUN. | last3 = Yamauchi | first3 = FI. | last4 = Baroni | first4 = RH. | title = Anastomosing hemangioma simulating renal cell carcinoma. | journal = Int Braz J Urol | volume = 43 | issue = 5 | pages = 987-989 | month = | year = | doi = 10.1590/S1677-5538.IBJU.2016.0653 | PMID = 28727378 }}</ref> | |||
==Gross== | ==Gross== | ||
Features: | Features: | ||
Line 10: | Line 44: | ||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Vascular tumour characterized by vessels that fuse/join (anastomose) | *Vascular tumour characterized by vessels that fuse/join (anastomose); described as ''splenic sinusoids-like''.<ref name=pmid27543862/> | ||
**+/-[[Hobnail morphology]]. | **+/-[[Hobnail morphology]]. | ||
**+/-Cytoplasmic hyaline globules. | |||
*+/-[[Extramedullary hematopoiesis]]. | |||
**[[Nucleated red blood cell]]s. | |||
**Megakaryocytes. | |||
Note: | Note: | ||
Line 18: | Line 56: | ||
DDx: | DDx: | ||
*[[Angiosarcoma]] - [[nuclear atypia]], more proliferative activity. | *[[Angiosarcoma]] - [[nuclear atypia]], more proliferative activity. | ||
*[[Angiomyolipoma]]. | |||
===Images=== | |||
<gallery> | |||
Image: Anastomosing hemangioma of the kidney -- low mag.jpg | AH - low mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney -- intermed mag.jpg | AH - intermed. mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney -- high mag.jpg | AH - high mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney -- very high mag.jpg | AH - very high mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney - alt -- extremely low mag.jpg | AH - extremely low mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney - alt -- very low mag.jpg | AH - very low mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney - alt -- low mag.jpg | AH - low mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney - alt -- intermed mag.jpg | AH - intermed. mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney - b -- intermed mag.jpg | AH - intermed. mag. (WC) | |||
Image: Anastomosing hemangioma of the kidney - b -- high mag.jpg | AH - high mag. (WC) | |||
</gallery> | |||
==IHC== | ==IHC== | ||
Line 33: | Line 87: | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Soft tissue lesions]] | [[Category:Soft tissue lesions]] | ||
[[Category:Kidney tumours]] |
Latest revision as of 13:33, 28 December 2018
Anastomosing hemangioma of the kidney | |
---|---|
Diagnosis in short | |
![]() Anastomosing hemangioma of the kidney. H&E stain. | |
| |
Synonyms | renal anastomosing hemangioma |
| |
LM | vascular tumour with architecture similar to splenic sinsoids, hobnailing, +/-hyaline globules, +/-extramedullary hematopoiesis |
LM DDx | angiosarcoma, other hemangiomas, other vascular tumours, angiomyolipoma |
IHC | CD34 +ve, CD31 +ve, HHV-8 |
Gross | brown/mahogany lesion, classically centered on medulla of kidney |
Grossing notes | total nephrectomy for tumour grossing, partial nephrectomy grossing |
Site | kidney |
| |
Associated Dx | +/-end stage renal disease |
Prevalence | very rare |
Radiology | may mimic renal cell carcinoma |
Prognosis | benign |
Clin. DDx | renal tumours |
Treatment | excision for definitive diagnosis? |
Anastomosing hemangioma of the kidney a rare benign vascular tumour of kidney that may mimic angiosarcoma.[1]
General
- Rare - case reports.
- The bigger category vascular tumours of the kidney is rare; in the world literature (as of 2015), according to Omiyale, there are approximately 40 angiosarcoma and 220 hemangiomas.[2]
- Typically seen in end stage renal disease.[3]
- May mimic renal cell carcinoma clinically.[4]
Gross
Features:
- Mahogany/brown - centered on medulla of kidney.[3]
Microscopic
Features:
- Vascular tumour characterized by vessels that fuse/join (anastomose); described as splenic sinusoids-like.[3]
- +/-Hobnail morphology.
- +/-Cytoplasmic hyaline globules.
- +/-Extramedullary hematopoiesis.
- Nucleated red blood cells.
- Megakaryocytes.
Note:
- Tumour may extend into surrounding adipose tissue.
DDx:
- Angiosarcoma - nuclear atypia, more proliferative activity.
- Angiomyolipoma.
Images
IHC
Features:[3]
- CD31 +ve.
- CD34 +ve.
- HHV8 -ve.
See also
References
- ↑ Montgomery, E.; Epstein, JI. (Sep 2009). "Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma.". Am J Surg Pathol 33 (9): 1364-9. doi:10.1097/PAS.0b013e3181ad30a7. PMID 19606014.
- ↑ Omiyale, AO. (Jul 2015). "Anastomosing hemangioma of the kidney: a literature review of a rare morphological variant of hemangioma.". Ann Transl Med 3 (11): 151. doi:10.3978/j.issn.2305-5839.2015.06.16. PMID 26244138.
- ↑ 3.0 3.1 3.2 3.3 Kuroda, N.; Ohe, C.; Deepika, S.; Yorita, K.; Mikami, S.; Furuya, M.; Nagashima, Y.; Hes, O. et al. (Jun 2016). "Review of renal anastomosing hemangioma with focus on clinical and pathological aspects.". Pol J Pathol 67 (2): 97-101. PMID 27543862.
- ↑ Silva, MA.; Fonseca, EKUN.; Yamauchi, FI.; Baroni, RH.. "Anastomosing hemangioma simulating renal cell carcinoma.". Int Braz J Urol 43 (5): 987-989. doi:10.1590/S1677-5538.IBJU.2016.0653. PMID 28727378.